Activity assays for flavoprotein oxidases: an overview [PDF]
Applied Microbiology and BiotechnologyFlavoprotein oxidases have found many biotechnological applications. For identifying and improving their characteristics, it is essential to have reliable and robust assay methodology available. The methodologies used to monitor their activity seem to be
Lars L. Santema, Marco W. Fraaije
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Flavoprotein monooxygenases for oxidative biocatalysis: recombinant expression in microbial hosts and applications [PDF]
Frontiers in Microbiology, 2014 External flavoprotein monooxygenases comprise a group of flavin-dependent oxidoreductases that catalyze the insertion of one atom of molecular oxygen into an organic substrate and the second atom is reduced to water. These enzymes are involved in a great
Romina D Ceccoli
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Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts [PDF]
Journal of Biotechnology, 2006 During the last decades a large number of flavin-dependent monooxygenases have been isolated and studied. This has revealed that flavoprotein monooxygenases are able to catalyze a remarkable wide variety of oxidative reactions such as regioselective ...
Willem J H Van Berkel, Marco W Fraaije
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Flavoprotein oxidases: classification and applications [PDF]
Applied Microbiology and Biotechnology, 2013 This review provides an overview of oxidases that utilise a flavin cofactor for catalysis. This class of oxidative flavoenzymes has shown to harbour a large number of biotechnologically interesting enzymes.
Mattevi, Andrea +10 more
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Electron transfer flavoprotein subunit beta suppresses hypoxia/reoxygenation-induced mitochondrial dysfunction and apoptosis in cardiomyocytes [PDF]
Journal of International Medical ResearchObjective This study aimed to investigate the role of the electron transfer flavoprotein subunit beta in myocardial ischemia–reperfusion injury.
Jing Liu
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Flavoprotein monooxygenases : Versatile biocatalysts
Biotechnology Advances, 2021 Flavoprotein monooxygenases (FPMOs) are single- or two-component enzymes that catalyze a diverse set of chemo-, regio- and enantioselective oxyfunctionalization reactions.
Eggerichs, Daniel +10 more
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Systematic Assessment of Uncoupling in Flavoprotein Oxidases and Monooxygenases [PDF]
ACS Sustainable Chemistry and Engineering, 2023 Flavin as a cofactor is an extremely versatile molecule that participates in a wide range of biochemical reactions. A special characteristic of the flavin cofactor, unique for a metal free cofactor, is its ability to react in its reduced form with ...
Marco W Fraaije
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The Oxidation of Thiols by Flavoprotein Oxidases: a Biocatalytic Route to Reactive Thiocarbonyls
Angewandte Chemie - International Edition, 2014 Flavoprotein oxidases are a diverse class of biocatalysts, most of which catalyze the oxidation of C[BOND]O, C[BOND]N, or C[BOND]C bonds. Flavoprotein oxidases that are known to catalyze the oxidation of C[BOND]S bonds are rare, being limited to enzymes ...
Tom A Ewing +2 more
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The VAO/PCMH flavoprotein family [PDF]
Archives of Biochemistry and Biophysics, 2017 The VAO/PCMH flavoprotein family consists of structurally homologous flavin-dependent enzymes that catalyze a wide range of chemical reactions. Family members share an architecture consisting of a conserved FAD-binding domain and a more variable ...
Tom A Ewing +2 more
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Can flavoprotein monooxygenases functionalize long-chain n-alkanes? [PDF]
PLoS ONELong-chain n-alkane functionalization is relevant for industrial and environmental applications, but it remains a significant challenge due to the inherent stability of their covalent bonds. Biocatalytic approaches offer promising strategies due to their
Raul Mireles +3 more
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