Flavins and Flavoproteins in the Neuroimmune Landscape of Stress Sensitization and Major Depressive Disorder [PDF]
Journal of Inflammation ResearchMatt Scott Schrier,1 Maria Igorevna Smirnova,2– 4 Daniel Paul Nemeth,1 Richard Carlton Deth,5 Ning Quan1,3 1Department of Biomedical Science, Charles E.
Schrier MS +4 more
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Fixing flavins: hijacking a flavin transferase for equipping flavoproteins with a covalent flavin cofactor [PDF]
J Am Chem Soc, 2023 Most flavin-dependent enzymes contain a dissociable flavin cofactor. We present a new approach for installing a covalent bond between a flavin cofactor and its hosting protein.
Hein, Wijma +5 more
core +3 more sources
Ferroptosis-Related Flavoproteins: Their Function and Stability [PDF]
International Journal of Molecular Sciences, 2021 Ferroptosis has been described recently as an iron-dependent cell death driven by peroxidation of membrane lipids. It is involved in the pathogenesis of a number of diverse diseases.
R Martin Vabulas
exaly +2 more sources
Assessing the Performance of Non-Equilibrium Thermodynamic Integration in Flavodoxin Redox Potential Estimation [PDF]
Molecules, 2023 Flavodoxins are enzymes that contain the redox-active flavin mononucleotide (FMN) cofactor and play a crucial role in numerous biological processes, including energy conversion and electron transfer.
Giuseppe Silvestri +6 more
doaj +2 more sources
Bioorthogonal Catalytic Activation of Platinum and Ruthenium Anticancer Complexes by FAD and Flavoproteins [PDF]
Angewandte Chemie - International Edition, 2018 Recent advances in bioorthogonal catalysis promise to deliver new chemical tools for performing chemoselective transformations in complex biological environments.
Silvia Alonso-De Castro +2 more
exaly +2 more sources
Evolution of function in the "two dinucleotide binding domains" flavoproteins. [PDF]
PLoS Computational Biology, 2007 Structural and biochemical constraints force some segments of proteins to evolve more slowly than others, often allowing identification of conserved structural or sequence motifs that can be associated with substrate binding properties, chemical ...
Sunil Ojha +2 more
doaj +2 more sources
6-4 photolyase differentially modulates transcription in the vertebrate circadian clock. [PDF]
PLoS GeneticsThe cryptochrome-photolyase family, a highly conserved set of flavoproteins, mediates many direct and indirect responses to sunlight. While the photolyases are light-dependent enzymes which catalyze photoreactivation repair of UV-induced DNA damage, the ...
Hongxiang Li +7 more
doaj +2 more sources
Flavoproteins as native and genetically encoded spin probes for in cell ESR spectroscopy [PDF]
Nature CommunicationsFlavin cofactors are attractive Electron Spin Resonance (ESR) probes for proteins because cellular reductants and light can generate their semiquinone states.
Timothée Chauviré +4 more
doaj +2 more sources
Genes Encoding A-Type Flavoproteins Are Essential for Photoreduction of O2 in Cyanobacteria
Current Biology, 2003 O2 photoreduction by photosynthetic electron transfer, the Mehler reaction [1], was observed in all groups of oxygenic photosynthetic organisms [2–4], but the electron transport chain mediating this reaction remains unidentified.
Dan Tchernov +2 more
exaly +2 more sources
Journal of Chemical Crystallography, 1994 In order to examine the possibility of hydrogen bonding around the flavin ring, an X-ray diffraction study of the title compound was undertaken.
Johan Wouters, F Moureau, G Evrard
exaly +2 more sources