Results 21 to 30 of about 8,960 (275)

Redox Titration of Flavoproteins: An Overview

, 2021
Redox titration of flavoproteins allows to detect and analyze (1) the determinants of the stabilization of individual redox forms of the flavin by the protein; (2) the binding of the redox-active cofactor to the protein; (3) the effects of other ...
Stefania Iametti, S. Iametti, F Bonomi, Francesco Bonomi   +3 more
core   +1 more source

Flavoprotein oxidases: classification and applications [PDF]

Applied Microbiology and Biotechnology, 2013
This review provides an overview of oxidases that utilise a flavin cofactor for catalysis. This class of oxidative flavoenzymes has shown to harbour a large number of biotechnologically interesting enzymes. Applications range from their use as biocatalysts for the synthesis of pharmaceutical compounds to the integration in biosensors.
Dijkman WP, de Gonzalo G, Fraaije MW, MATTEVI, ANDREA   +3 more
openaire   +4 more sources

3D imaging of the mitochondrial redox state of rat hearts under normal and fasting conditions [PDF]

Journal of Innovative Optical Health Sciences, 2014
The heart requires continuous ATP availability that is generated in the mitochondria. Although studies using the cell culture and perfused organ models have been carried out to investigate the biochemistry in the mitochondria in response to a change in ...
He N. Xu, Rong Zhou, Lily Moon, Min Feng, Lin Z. Li   +4 more
doaj   +1 more source

Vitamin B2 enables regulation of fasting glucose availability

eLife, 2023
Flavin adenine dinucleotide (FAD) interacts with flavoproteins to mediate oxidation-reduction reactions required for cellular energy demands. Not surprisingly, mutations that alter FAD binding to flavoproteins cause rare inborn errors of metabolism (IEMs)
Peter M Masschelin, Pradip Saha, Scott A Ochsner, Aaron R Cox, Kang Ho Kim, Jessica B Felix, Robert Sharp, Xin Li, Lin Tan, Jun Hyoung Park, Liping Wang, Vasanta Putluri, Philip L Lorenzi, Alli M Nuotio-Antar, Zheng Sun, Benny Abraham Kaipparettu, Nagireddy Putluri, David D Moore, Scott A Summers, Neil J McKenna, Sean M Hartig   +20 more
doaj   +1 more source

Biosynthesis of flavoproteins [PDF]

, 1987
published
Yagi, Kunio, Inagaki, Taisuke, Ichihara, Chikako, Koshizaka, Takuya, Ohishi, Nobuko, Tsukagoshi, Norihiro, Udaka, Shigezo, Nishikimi, Morimitsu, Ozawa, Takayuki, Ghisla, Sandro   +9 more
openaire   +2 more sources

The Membrane-Bound C Subunit of Reductive Dehalogenases: Topology Analysis and Reconstitution of the FMN-Binding Domain of PceC

Frontiers in Microbiology, 2018
Organohalide respiration (OHR) is the energy metabolism of anaerobic bacteria able to use halogenated organic compounds as terminal electron acceptors.
Géraldine F. Buttet, Mathilde S. Willemin, Romain Hamelin, Aamani Rupakula, Julien Maillard   +4 more
doaj   +1 more source

Involvement of a flavoprotein, acetohydroxyacid synthase, in growth and riboflavin production in riboflavin-overproducing Ashbya gossypii mutant

Microbial Cell Factories, 2023
Background Previously, we isolated a riboflavin-overproducing Ashbya gossypii mutant (MT strain) and discovered some mutations in genes encoding flavoproteins.
Tatsuya Kato, Mai Kano, Ami Yokomori, Junya Azegami, Hesham A. El Enshasy, Enoch Y. Park   +5 more
doaj   +1 more source

Assays of D-Amino Acid Oxidase Activity

Frontiers in Molecular Biosciences, 2018
D-amino acid oxidase (DAAO) is a well-known flavoenzyme that catalyzes the oxidative FAD-dependent deamination of D-amino acids. As a result of the absolute stereoselectivity and broad substrate specificity, microbial DAAOs have been employed as ...
Elena Rosini, Elena Rosini, Laura Caldinelli, Laura Caldinelli, Luciano Piubelli, Luciano Piubelli   +5 more
doaj   +1 more source

New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases

Nutrition & Metabolism, 2023
Riboflavin, or vitamin B2, is an essential nutrient that serves as a precursor to flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). The binding of the FAD and/or FMN cofactors to flavoproteins is critical for regulating their assembly ...
Chiara Murgia, Ankush Dehlia, Mark A. Guthridge   +2 more
doaj   +1 more source

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

Redox Biology, 2021
The multifunctional nature of human flavoproteins is critically linked to their ability to populate multiple conformational states. Ligand binding, post-translational modifications and disease-associated mutations can reshape this functional landscape ...
Juan Luis Pacheco-Garcia, Ernesto Anoz-Carbonell, Pavla Vankova, Adithi Kannan, Rogelio Palomino-Morales, Noel Mesa-Torres, Eduardo Salido, Petr Man, Milagros Medina, Athi N. Naganathan, Angel L. Pey   +10 more
doaj   +1 more source