Results 21 to 30 of about 5,671 (202)
Redox Biology, 2021 The multifunctional nature of human flavoproteins is critically linked to their ability to populate multiple conformational states. Ligand binding, post-translational modifications and disease-associated mutations can reshape this functional landscape ...
Juan Luis Pacheco-Garcia +10 more
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Assays of D-Amino Acid Oxidase Activity
Frontiers in Molecular Biosciences, 2018 D-amino acid oxidase (DAAO) is a well-known flavoenzyme that catalyzes the oxidative FAD-dependent deamination of D-amino acids. As a result of the absolute stereoselectivity and broad substrate specificity, microbial DAAOs have been employed as ...
Elena Rosini +5 more
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Frontiers in Microbiology, 2018 Comparative genome analyses have led to the discovery and characterization of novel flavin- and folate-dependent methyltransferases that mainly function in DNA precursor synthesis and post-transcriptional RNA modification by forming (ribo) thymidylate ...
Hannu Myllykallio +4 more
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Evolution of function in the "two dinucleotide binding domains" flavoproteins. [PDF]
PLoS Computational Biology, 2007 Structural and biochemical constraints force some segments of proteins to evolve more slowly than others, often allowing identification of conserved structural or sequence motifs that can be associated with substrate binding properties, chemical ...
Sunil Ojha +2 more
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Open Biology, 2021 Iron-sulfur (Fe-S) flavoproteins form a broad and growing class of complex, multi-domain and often multi-subunit proteins coupling the most ancient cofactors (the Fe-S clusters) and the most versatile coenzymes (the flavin coenzymes, FMN and FAD).
Maria Antonietta Vanoni
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Photolyase Production and Current Applications: A Review
Molecules, 2022 The photolyase family consists of flavoproteins with enzyme activity able to repair ultraviolet light radiation damage by photoreactivation. DNA damage by the formation of a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4 ...
Diana Ramírez-Gamboa +12 more
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BBA Advances, 2023 In recent years, studies have shown that a large number of bacteria secrete multi-flavinylated proteins. The exact roles and properties, of these extracellular flavoproteins that contain multiple covalently anchored FMN cofactors, are still largely ...
Yapei Tong +4 more
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From identification of fluorescent flavoproteins to mitochondrial redox indicators in intact tissues [PDF]
Journal of Innovative Optical Health Sciences, 2014 Development of the use of flavin and nicotinamide-adenine nucleotide fluorescence in monitoring the redox state of the free mitochondrial NADH/NAD+ couple in cells, tissues and organs is reviewed.
Ilmo E. Hassinen
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Flavoprotein monooxygenases: Versatile biocatalysts
Biotechnology Advances, 2021 Flavoprotein monooxygenases (FPMOs) are single- or two-component enzymes that catalyze a diverse set of chemo-, regio- and enantioselective oxyfunctionalization reactions. In this review, we describe how FPMOs have evolved from model enzymes in mechanistic flavoprotein research to biotechnologically relevant catalysts that can be applied for the ...
Paul, Caroline E. +4 more
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Molecules, 2018 The 19th International Symposium on Flavins and Flavoproteins was held from 2–6 July 2017 in Groningen, The Netherlands.[...]
Willem J.H. van Berkel
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