Results 41 to 50 of about 29,105 (237)

Activation of a Flavoprotein by Proteolysis

Journal of Biological Chemistry, 1989
Chymotryptic digestion of brain pyridoxine-5-P oxidase brings about a 4-fold enhancement of the catalytic power (Vmax/KM) using pyridoxine-5-P as substrate in the assay mixtures. The chymotrypsin-treated enzyme is less susceptible to inhibition by pyridoxal-5-P than the native enzyme.
Y T, Kim, J E, Churchich
openaire   +2 more sources

Distribution in Different Organisms of Amino Acid Oxidases with FAD or a Quinone As Cofactor and Their Role as Antimicrobial Proteins in Marine Bacteria

Marine Drugs, 2015
Amino acid oxidases (AAOs) catalyze the oxidative deamination of amino acids releasing ammonium and hydrogen peroxide. Several kinds of these enzymes have been reported.
Jonatan C. Campillo-Brocal, Patricia Lucas-Elío, Antonio Sanchez-Amat   +2 more
doaj   +1 more source

Archaeal LOV domains from Lake Diamante: first functional characterization of a halo-adapted photoreceptor

Frontiers in Microbiology
High-altitude Andean lakes (HAALs) represent polyextreme environments where diverse photoinduced processes have been documented. In this study, we investigated Light-Oxygen-Voltage (LOV) photoreceptors and identified 28 archaeal sequences from Lake ...
Lorena Valle, Lorena Valle, Yonathan J. Coronel, Yonathan J. Coronel, Guillermina E. Bravo, Joaquín A. Díaz, Virginia Helena Albarracín, Virginia Helena Albarracín, María E. Farías, Inés Abatedaga   +9 more
doaj   +1 more source

VpStyA1/VpStyA2B of Variovorax paradoxus EPS: An Aryl Alkyl Sulfoxidase Rather than a Styrene Epoxidizing Monooxygenase

Molecules, 2018
Herein we describe the first representative of an E2-type two-component styrene monooxygenase of proteobacteria. It comprises a single epoxidase protein (VpStyA1) and a two domain protein (VpStyA2B) harboring an epoxidase (A2) and a FAD-reductase (B ...
Dirk Tischler, Ringo Schwabe, Lucas Siegel, Kristin Joffroy, Stefan R. Kaschabek, Anika Scholtissek, Thomas Heine   +6 more
doaj   +1 more source

Assigning function to active site residues of Schistosoma mansoni thioredoxin/glutathione reductase from analysis of transient state reductive half-reactions with variant forms of the enzyme

Frontiers in Molecular Biosciences, 2023
Thioredoxin/glutathione reductase (TGR) from the platyhelminthic parasitic worms has recently been identified as a drug target for the treatment of schistosomiasis.
Madison M. Smith, Graham R. Moran
doaj   +1 more source

Genome Sequence of Stenotrophomonas maltophilia PML168, Which Displays Baeyer-Villiger Monooxygenase Activity

, 2012
Stenotrophomonas maltophilia PML168 was isolated from Wembury Beach on the English Coast from a rock pool following growth and selection on agar plates.
Muhling, M, Weynberg, KD, Mavromatis, K, Grogan, G, Nissimov, Jozef, Jensen, Chantel N., Allen, MJ, Allen, Michael J., Trivedi, Urmi, Mavromatis, Konstantinos, Tait, Karen, Jensen, C, Ali, ST, Nissimov, JI, Tait, K, Gharbi, K, Gharbi, Karim, Muehling, Martin, Bradley, Claire, Ali, Sohail T., Trivedi, U, Grogan, Gideon, Bradley, C, Weynberg, Karen   +23 more
core   +1 more source

Engineering an Artificial Flavoprotein Magnetosensor [PDF]

Journal of the American Chemical Society, 2016
Migratory birds use the Earth's magnetic field as a source of navigational information. This light-dependent magnetic compass is thought to be mediated by cryptochrome proteins in the retina. Upon light activation, electron transfer between the flavin adenine dinucleotide cofactor and tryptophan residues leads to the formation of a spin-correlated ...
Chris Bialas, Lauren E. Jarocha, Kevin B. Henbest, Tilo M. Zollitsch, Goutham Kodali, Christiane R. Timmel, Stuart R. Mackenzie, P. Leslie Dutton, Christopher C. Moser, P. J. Hore   +9 more
openaire   +2 more sources

KillerRed protein based in vivo photodynamic therapy and corresponding tumor metabolic imaging [PDF]

Journal of Innovative Optical Health Sciences, 2016
Photodynamic therapy (PDT) gains wide attention as a useful therapeutic method for cancer. It is mediated by the oxygen and photosensitizer under the specific light irradiation to produce the reactive oxygen species (ROS), which induce cellular toxicity ...
Qiaoya Lin, Shuang Sha, Fei Yang, Honglin Jin, Zhihong Zhang   +4 more
doaj   +1 more source

Pyridine Nucleotide Coenzyme Specificity of p-Hydroxybenzoate Hydroxylase and Related Flavoprotein Monooxygenases

Frontiers in Microbiology, 2018
p-Hydroxybenzoate hydroxylase (PHBH; EC 1.14.13.2) is a microbial group A flavoprotein monooxygenase that catalyzes the ortho-hydroxylation of 4-hydroxybenzoate to 3,4-dihydroxybenzoate with the stoichiometric consumption of NAD(P)H and oxygen.
Adrie H. Westphal, Dirk Tischler, Florian Heinke, Sarah Hofmann, Janosch A. D. Gröning, Dirk Labudde, Willem J. H. van Berkel   +6 more
doaj   +1 more source

Mechanisms of flavoprotein‐catalyzed reactions [PDF]

European Journal of Biochemistry, 1989
Flavoproteins are a class of enzymes catalyzing a very broad spectrum of redox processes by different chemical mechanisms. This review describes the best studied of these mechanisms and discusses factors possibly governing reactivity and specificity.
Ghisla, Sandro, Massey, Vincent
openaire   +5 more sources