Results 1 to 10 of about 10,776 (205)

A biomimetic redox flow battery based on flavin mononucleotide [PDF]

Nature Communications, 2016
Redox flow batteries using organic active materials are highly sought after because of their potential to satisfy low cost and sustainability requirements. Here, the authors report a biomimetic flow battery based on flavin mononucleotide and a hydrotrope
Akihiro Orita, Michael G. Verde, Masanori Sakai, Ying Shirley Meng   +3 more
doaj   +10 more sources

Affinity-Based Profiling of the Flavin Mononucleotide Riboswitch. [PDF]

J Am Chem Soc, 2022
Riboswitches are structural RNA elements that control gene expression. These naturally occurring RNA sensors are of continued interest as antibiotic targets, molecular sensors, and functional elements of synthetic circuits. Here, we describe affinity-based profiling of the flavin mononucleotide (FMN) riboswitch to characterize ligand binding and ...
Crielaard S, Maassen R, Vosman T, Rempkens I, Velema WA.   +4 more
europepmc   +7 more sources

Flavin Mononucleotide as a Biomarker of Organ Quality—A Pilot Study [PDF]

Transplantation Direct, 2020
Background. Flavin mononucleotide (FMN), released from damaged mitochondrial complex I during hypothermic liver perfusion, has been shown to be predictive of 90-day graft loss. Normothermic machine perfusion (NMP) and normothermic regional perfusion (NRP)
Lu Wang, MRCS, Emily Thompson, MRCS, Lucy Bates, BSc, Thomas L. Pither, BSc, Sarah A. Hosgood, PhD, Michael L. Nicholson, DSc, Christopher J.E. Watson, MD, Colin Wilson, PhD, Andrew J. Fisher, PhD, Simi Ali, PhD, John H. Dark, FRCS   +10 more
doaj   +5 more sources

Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. [PDF]

ACS Chem Biol, 2018
The flavin mononucleotide (FMN) riboswitch is an emerging target for the development of novel RNA-targeting antibiotics. We previously discovered an FMN derivative, 5FDQD, that protects mice against diarrhea-causing Clostridium difficile bacteria. Here, we present the structure-based drug design strategy that led to the discovery of this fluoro-phenyl ...
Vicens Q, Mondragón E, Reyes FE, Coish P, Aristoff P, Berman J, Kaur H, Kells KW, Wickens P, Wilson J, Gadwood RC, Schostarez HJ, Suto RK, Blount KF, Batey RT.   +14 more
europepmc   +5 more sources

Lactobacillus plantarum Generate Electricity through Flavin Mononucleotide-Mediated Extracellular Electron Transfer to Upregulate Epithelial Type I Collagen Expression and Thereby Promote Microbial Adhesion to Intestine [PDF]

Biomedicines, 2023
The mechanism behind how flavin mononucleotide (FMN)-producing bacteria attach to a host intestine remains unclear. In order to address this issue, this study isolated the Gram-positive bacteria Lactobacillus plantarum from Mongolian fermented Airag ...
Binderiya Ganzorig, Enkhbat Zayabaatar, Minh Tan Pham, Shinta Marito, Chun-Ming Huang, Yu-Hsiang Lee   +5 more
doaj   +2 more sources

Photodynamic therapy of melanoma by blue-light photoactivation of flavin mononucleotide [PDF]

Scientific Reports, 2019
Melanoma is one of the most aggressive and lethal form of cancer. Photodynamic therapy (PDT) is a clinically approved technique for cancer treatment, including non-melanoma skin cancer.
R. A. Akasov, N. V. Sholina, D. A. Khochenkov, A. V. Alova, P. V. Gorelkin, A. S. Erofeev, A. N. Generalova, E. V. Khaydukov   +7 more
doaj   +2 more sources

Flavin Biosynthesis Enhances Extracellular Electron Transfer in Bioengineered Escherichia coli [PDF]

Advanced Science
Advancements in bioengineering have unlocked new microbial electrochemical applications in energy, sensing, remediation, and synthesis. Key to realizing these technologies is the engineering of conduits in metabolically versatile microbes like ...
Mohammed Mouhib, Melania Reggente, Hanxuan Wang, Charlotte Roullier, Ardemis A. Boghossian   +4 more
doaj   +2 more sources

Flavin-dependent monooxygenases as versatile biocatalysts in biomanufacturing: mechanisms, engineering, and applications [PDF]

Biotechnology for Biofuels and Bioproducts
Flavin-dependent monooxygenases (FMOs) are versatile oxidative biocatalysts that catalyze a wide array of oxygenation reactions, such as hydroxylation, epoxidation, Baeyer–Villiger oxidation, and halogenation.
Yong Li, Ling Zhao, Xin Pu, Biao Geng, Wei Liu, Jie Gao, Xiaowei Peng, Yejun Han   +7 more
doaj   +2 more sources

Caffeic Acid Inhibits the Formation of 7-Carboxyheptyl Radicals from Oleic Acid under Flavin Mononucleotide Photosensitization by Scavenging Singlet Oxygen and Quenching the Excited State of Flavin Mononucleotide [PDF]

Molecules, 2014
We examined the effects of caffeic acid (CA) and related compounds on 7-carboxyheptyl radical formation. This analysis was performed using a standard D2O reaction mixture containing 4.3 mM oleic acid, 25 μM flavin mononucleotide (FMN), 160 mM phosphate ...
Marie Asano, Hideo Iwahashi
doaj   +2 more sources

Cyclic-FMN Is a Detectable, Putative Intermediate of FAD Metabolism [PDF]

Biomolecules
Free flavin adenine dinucleotide (FAD) is metabolized to flavin mononucleotide (FMN) and adenine monophosphate (AMP) by hydrolases and to 4′,5′-cyclic phosphoriboflavin (cFMN) and AMP by the triose kinase FMN cyclase (TKFC).
Luxene Belfleur, Juha P. Kallio, Wito Richter, Natalie R. Gassman, Mathias Ziegler, Marie E. Migaud   +5 more
doaj   +2 more sources