Results 31 to 40 of about 29,105 (237)
Molecules, 2018 FAD synthase (FADS, EC 2.7.7.2) is the last essential enzyme involved in the pathway of biosynthesis of Flavin cofactors starting from Riboflavin (Rf). Alternative splicing of the human FLAD1 gene generates different isoforms of the enzyme FAD synthase ...
Piero Leone +10 more
doaj +1 more source
Characterization of succinate dehydrogenase flavoprotein from Staphylococcus aureus ATCC 12600 [PDF]
Journal of Clinical and Scientific Research, 2013 Background: Staphylococcus aureus possesses complete tricarboxylic acid (TCA) cycle. Succinate dehydrogenase (SDH) links TCA cycle with electron transport chain and could therefore be an ideal target in the development of new antimicrobials.
V. Swarupa +12 more
doaj
Antioxidants, 2022 Allosterism is a common phenomenon in protein biochemistry that allows rapid regulation of protein stability; dynamics and function. However, the mechanisms by which allosterism occurs (by mutations or post-translational modifications (PTMs)) may be ...
Juan Luis Pacheco-Garcia +9 more
doaj +1 more source
Enhancing The Photocatalytic Conversion Of Pt(IV) Substrates By Flavoprotein Engineering
, 2021 Our recent work demonstrates that certain flavoproteins can catalyze the redox activation of Pt(IV) prodrug complexes under light irradiation. Herein, we used site directed mutagenesis on the mini Singlet Oxygen Generator (mSOG) to modulate the ...
Juan, Gurruchaga-Pereda +7 more
core +1 more source
Reservoir Computing‐Based Glucose Sensing With an Enzymatic Reaction Network
Angewandte Chemie, EarlyView.Glucose oxidase (GOx) catalyzes the conversion of glucose into gluconic acid, lowering the solution pH. The extent of pH change depends on the glucose input and directly modulates the activity of the enzyme reservoir. Glucose levels can be sensed by monitoring the changes in the enzymatic reservoir output, that is, the generation of peptide fragments ...
Souvik Ghosh +3 more
wiley +2 more sources
Functional Impact of the N-terminal Arm of Proline Dehydrogenase from Thermus thermophilus
Molecules, 2018 Proline dehydrogenase (ProDH) is a ubiquitous flavoenzyme that catalyzes the oxidation of proline to Δ1-pyrroline-5-carboxylate. Thermus thermophilus ProDH (TtProDH) contains in addition to its flavin-binding domain an N-terminal arm, consisting of ...
Mieke M. E. Huijbers +5 more
doaj +1 more source
REDOX IMAGING OF THE p53-DEPENDENT MITOCHONDRIAL REDOX STATE IN COLON CANCER EX VIVO [PDF]
Journal of Innovative Optical Health Sciences, 2013 The mitochondrial redox state and its heterogeneity of colon cancer at tissue level have not been previously reported. Nor has how p53 regulates mitochondrial respiration been measured at (deep) tissue level, presumably due to the unavailability of the ...
HE N. XU +5 more
doaj +1 more source
Methyl rotors in flavoproteins
Phys. Chem. Chem. Phys., 2014 ENDOR evidence shows that methyl groups in flavin behave as quantum locked rotors.
Jesús I. Martínez +3 more
openaire +3 more sources
Neurobiology of Disease, 2018 Myotonic dystrophy (DM) is a progressive, multisystem disorder affecting skeletal muscle, heart, and central nervous system. In both DM1 and DM2, microsatellite expansions of CUG and CCUG RNA repeats, respectively, accumulate and disrupt functions of ...
Gang Chen +6 more
doaj +1 more source
Fluorescence spectroscopic detection of mitochondrial flavoprotein redox oscillations and transient reduction of the NADPH oxidase-associated flavoprotein in leukocytes [PDF]
, 2004 Steady-state and time-resolved fluorescence spectroscopy and fluorescence microscopy of leukocyte flavoproteins have been performed. Both living human peripheral blood monocytes and neutrophils have been utilized as experimental models, as the former ...
Kindzelskii, Andrei L., Petty, Howard R.
core +1 more source