Results 71 to 80 of about 5,671 (202)
Journal of Fish Biology, EarlyView.Abstract Antimicrobial peptides (AMPs) are key components of the innate immune system in fish, providing rapid protection against microbial pathogens. Among these, the liver‐expressed antimicrobial peptides (LEAPs), comprising LEAP‐1 (hepcidin; HAMP) and LEAP‐2, play central roles in host defence and iron regulation.
Roberta Marcoli +6 more
wiley +1 more source
Stretch Induced Hyperexcitability of Mice Callosal Pathway
Frontiers in Cellular Neuroscience, 2015 Memory and learning are thought to result from changes in synaptic strength. Previous studies on synaptic physiology in brain slices have traditionally been focused on biochemical processes.
Anthony eFan +6 more
doaj +1 more source
CO2‐sensitive K+ channel traffic affects stomata and whole‐plant water use
Journal of Integrative Plant Biology, EarlyView.CO2‐responsive regulation of membrane trafficking influences the density of the potassium ion (K+) channel KAT1 at the plasma membrane. CO2‐sensitive traffic, dependent on trafficking by the SNARE SYP121, impacts stomatal gas exchange and plant growth.
Zhiyi Yu +4 more
wiley +1 more source
Origin and Evolution of Flavin-Based Electron Bifurcating Enzymes
Frontiers in Microbiology, 2018 Twelve evolutionarily unrelated oxidoreductases form enzyme complexes that catalyze the simultaneous coupling of exergonic and endergonic oxidation–reduction reactions to circumvent thermodynamic barriers and minimize free energy loss in a process known ...
Saroj Poudel +6 more
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Molecular Microbiology, EarlyView.The Lyme disease agent Borrelia burgdorferi has limited metabolic capabilities and depends on salvage of riboflavin via the BB0316‐BB0319 transport system for generation of critical flavin cofactors FMN and FAD. Riboflavin is important for NAD+ regeneration to fuel glycolysis.
Anna M. Schulz +3 more
wiley +1 more source
Photochemistry of CryB from Rhodobacter sphaeroides
Photochemistry and Photobiology, EarlyView.Elucidation of the photochemistry of CryB from Rhodobacter sphaeroides was achieved from the nanosecond to second timescale. A fast (<5 ns) deprotonation of the terminal electron donor Trp338 and the involvement of Tyr337 in photoreduction have been revealed.
Christopher Einholz +6 more
wiley +1 more source
Frontiers in Microbiology, 2018 Flavin-based electron bifurcation is a newly discovered mechanism, by which a hydride electron pair from NAD(P)H, coenzyme F420H2, H2, or formate is split by flavoproteins into one-electron with a more negative reduction potential and one with a more ...
Wolfgang Buckel, Rudolf K. Thauer
doaj +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Objective The clinical manifestation and electron transfer flavoprotein dehydrogenase (ETFDH) gene mutation of riboflavin-responsive lipid storage myopathy were analyzed for early diagnosis and treatment.mutation of riboflavin-responsive lipid storage
Ji-qing CAO +11 more
doaj
Respiratory Research, 2006 Background Acute alveolar hypoxia causes pulmonary vasoconstriction (HPV) which serves to match lung perfusion to ventilation. The underlying mechanisms are not fully resolved yet.
Goldenberg Anna +5 more
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Substrate‐specific mitochondrial dysfunction and metabolomic profiles in type 2 diabetic rat hearts
Experimental Physiology, EarlyView.Abstract Type 2 diabetes (T2D) greatly alters cardiac fuel handling, yet how mitochondrial function adapts to the diabetic substrate environment remains unclear. This study investigated substrate‐specific cardiac mitochondrial bioenergetics from a T2D rat model induced by a high‐fat diet and low‐dose streptozotocin.
Toan Pham
wiley +1 more source