Results 91 to 100 of about 5,671 (202)

Azurins With Tunable Reduction Potentials as Redox Mediators for Extracellular Electron Transfer

open access: yesChemBioChem, Volume 27, Issue 14, 29 July 2026.
Electroactive microbe Shewanella oneidensis reduced non‐native electron transfer protein, azurin, via extracellular electron transfer (EET) with dependence on azurin redox potential. Utilizing azurin in EET‐driven bio‐(electro)catalysis improved fuel cell current and accelerated textile dye decolorization.
Alexis J. Holwerda   +4 more
wiley   +1 more source

Thioredoxin Reductase as a Target for Antibacterial Gold Compounds in Burkholderia cenocepacia: Disclosing the Molecular Basis of Enzyme Inhibition

open access: yesChemBioChem, Volume 27, Issue 13, 14 July 2026.
The molecular basis of thioredoxin reductase inhibition by antibacterial gold(I) compounds is disclosed. X‐ray crystallography and high‐resolution ESI‐MS reveal selective gold coordination to catalytically relevant cysteine residues of Bc‐TrxR, leading to stable protein–gold adducts and disruption of enzyme redox activity.
Stefano Zineddu   +7 more
wiley   +1 more source

Life on Mars? The physiological perspective

open access: yes
Experimental Physiology, EarlyView.
Ronan M. G. Berg, Damian M. Bailey
wiley   +1 more source

Furagin Derivatives—Nitrofuran‐Based Hydrazones as Potential Dual Inhibitors of Thioredoxin Reductase and Carbonic Anhydrases

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
Nitrofuran‐based hydrazones derived from furagin are developed as dual inhibitors of thioredoxin reductase 1 and cancer‐associated carbonic anhydrases IX and XII. The series shows selective enzyme inhibition with reduced off‐target carbonic anhydrase (CA) I/II activity, while lead compound 7g exhibits potent TrxR1 inhibition and moderate anticancer ...
Aleksandrs Pustenko   +6 more
wiley   +1 more source

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 7, July 2026.
Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus   +5 more
wiley   +1 more source

Coenzyme Acceptance in Ene‐Reductases From Herbaspirillum seropedicae

open access: yesChemistryEurope, Volume 4, Issue 7, July 2026.
Ene‐reductases HSI and HSII from the beta‐proteobacterium Herbaspirillum seropedicae show promiscuity towards the coenzymes NADH and NADPH and efficiently reduce maleimides. Ancestral sequence reconstruction, kinetic characterisation and structural analysis suggest that oligomerisation contributes to the evolution of coenzyme acceptance. Ene‐reductases
Karishma Shah   +6 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva   +5 more
wiley   +1 more source

Structural basis of regioselective double halogenation of the β‐carboline tryptoline by the single‐component halogenase AetF

open access: yesActa Crystallographica Section D, Volume 82, Issue 7, Page 836-844, July 2026.
A structure of the flavin‐dependent single‐component tryptophan halogenase AetF bound to the non‐native tricyclic substrate tryptoline reveals a binding pose analogous to l‐tryptophan that directs C6‐first halogenation. Product analysis identifies 6,8‐dibromotryptoline as the final product.Flavin‐dependent halogenases (FDHs) offer a biocatalytic route ...
Simon Bork   +3 more
wiley   +1 more source

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

open access: yesPlant Biotechnology Journal, Volume 24, Issue 7, Page 4577-4598, July 2026.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan   +15 more
wiley   +1 more source

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