Results 61 to 70 of about 8,960 (275)

Engineering pyranose 2-oxidase for modified oxygen reactivity.

PLoS ONE, 2014
Pyranose 2-oxidase (POx), a member of the GMC family of flavoproteins, catalyzes the regioselective oxidation of aldopyranoses at position C2 to the corresponding 2-ketoaldoses.
Dagmar Brugger, Iris Krondorfer, Christopher Shelswell, Benjamin Huber-Dittes, Dietmar Haltrich, Clemens K Peterbauer   +5 more
doaj   +1 more source

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger, Elric Zweck, Constanze Moos, Patrick Horn, Fabian Voß, Heinz‐Peter Schultheiss, Jacob Eifer Møller, Udo Boeken, Hug Aubin, Artur Lichtenberg, Malte Kelm, Michael Roden, Amin Polzin, Ralf Westenfeld, Julia Szendroedi, Daniel Scheiber   +15 more
wiley   +1 more source

Antibacterial properties of the mammalian L-amino acid oxidase IL4I1. [PDF]

PLoS ONE, 2013
L-amino acid oxidases (LAAO) are flavoproteins that catalyze the oxidative deamination of L-amino acids to a keto-acid along with the production of H₂O₂ and ammonia.
Marie-Line Puiffe, Isabelle Lachaise, Valérie Molinier-Frenkel, Flavia Castellano   +3 more
doaj   +1 more source

Light‐Driven Butyrate Production by a Probiotic Clostridium tyrobutyricum Enabled by a Cell‐Semiconductor Hybrid Interface

Food Chemistry International, EarlyView.
This schematic illustrates a light‐driven biohybrid system where CdS nanoparticles, mineralized on the probiotic Clostridium tyrobutyricum, inject photoelectrons to elevate intracellular NADH. This boosts the flux through key NADH‐dependent enzymes (GapA, Hbd, and Bcd), reprogramming metabolism to enhance butyrate yield by 33.2% and selectivity to 95.7%
Qianru Zhao, Zhihan Yang, Bowen Shen, Ling Jiang   +3 more
wiley   +1 more source

Ligand Binding in Allosteric Flavoproteins: Part 2. Quantitative Analysis of the Redox-Dependent Interaction of the Apoptosis-Inducing Factor (AIF) with Its Protein Partner

, 2021
To perform their action usually flavoproteins interact transiently with a variety of molecular partners, whose binding is reciprocally affected and often controlled by the redox state of the bound flavin cofactor.
Aliverti, Alessandro, Eloise Mastrangelo, Delia Tarantino, Tarantino, Delia, Mastrangelo, Eloise, Cocomazzi, Paolo, Alessandro Aliverti, Paolo Cocomazzi   +7 more
core   +1 more source

Assessing the potential of photosensitizing flavoproteins as tags for correlative microscopy [PDF]

, 2016
Photosensitizing flavoproteins have great potential as tags for correlative light and electron microscopy (CLEM). We examine the photostability of miniSOG mutants and their ability to photooxidize diaminobenzidine, both key aspects for CLEM.
Nonell, Santi, Torra, Joaquim, Ruiz González, Rubén, Rodríguez-Pulido, Alberto, Cortajarena, Aitziber L., Flors, Cristina   +5 more
core   +2 more sources

Bowel viability assessment during surgery (review of the literature)

Вестник хирургии имени И.И. Грекова, 2020
The problem of bowel viability assessment during surgery is still opened. High value predictive and economically available technique is thought to decrease postoperative morbidity and mortality during elective and urgent abdominal surgery.
A. A. Zacharenko, M. A. Belyaev, A. A. Trushin, D. A. Zaytcev, R. V. Kursenko   +4 more
doaj   +1 more source

The X‐Ray Crystal Structure of BorF, the Flavin Reductase Subunit of a Two‐Component Flavin‐Dependent Tryptophan Halogenase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma, Emily W. Rady, Aravinda J. de Silva, John J. Bellizzi III   +3 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Molecularly Engineered 2D Xene Heterostructures With Implanted Peroxidase‐Like Activity for Mimicking Enzyme Functions

Small Methods, EarlyView.
A modular electropolymerization strategy is used to covalently graft a vinyl‐terminated Co(II) molecular catalyst onto allyl 2D germanane. This molecular programming approach yields a 2D Xene nanozyme with implanted peroxidase‐like activity, enabling sensitive and selective electrochemical detection of hydrogen peroxide and the monitoring of ...
Yiming Lei, Xavier Sala, Jordi García‐Antón, Jose Muñoz   +3 more
wiley   +1 more source