Monographies on drugs, which are frequently analysed in the course of Therapeutic Drug Monitoring Monographien über Medikamente, die regelmässig im Rahmen des Therapeutic Drug Monitorings analysiert werden [PDF]
, 2017 In 1995 the working group "Drug Monitoring” of the Swiss Society of Clinical Chemistry (SSCC) has already published a printed version of drug monographs, which are now newly compiled and presented in a standardised manner.
Fathi, M. +7 more
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Frontiers in PharmacologyFlecainide acetate is a Class 1c anti-arrhythmic with a potent sodium voltage gated channel blockade which is utilized for the second-line treatment of tachyarrhythmias in children and adults.
Ronald Palmen +6 more
doaj +1 more source
Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6) [PDF]
, 2017 Aims Short QT syndrome (SQTS) is a genetically determined ion-channel disorder, which may cause malignant tachyarrhythmias and sudden cardiac death. Thus far, mutations in five different genes encoding potassium and calcium channel subunits have been ...
Abriel, Hugues +14 more
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Incidence of All-Cause, Cardiovascular, and Atrial Fibrillation-Related Hospitalizations
JACC: AdvancesBackground: Atrial fibrillation (AF) is associated with an increased risk of hospital admission, but few data on reasons for hospitalization and on the role of anti-arrhythmic drugs are available.
Danilo Menichelli, MD +12 more
doaj +1 more source
A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation [PDF]
, 2017 Objective Brugada syndrome (BS) is an inherited electrical cardiac disorder characterized by right bundle branch block pattern and ST segment elevation in leads V1 to V3 on surface electrocardiogram that can potentially lead to malignant ventricular ...
Brink, Marijke +9 more
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Incidence and predictors of premature ventricular complexes following catheter ablation for atrial fibrillation [PDF]
, 2017 BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia, and previous studies have focused on the epidemiology, mechanisms and risk factors for this global disease (Ryder and Benjamin 1999). Various studies have examined the mechanism,
Harvey, Joshua
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Class IC Atrial Flutter Presenting as a Wide Complex Tachycardia: Lessons from a Case Report
Iberoamerican Journal of MedicineFlecainide is an established antiarrhythmic agent for atrial fibrillation (AF), but monotherapy without atrioventricular nodal blockade can precipitate atrial flutter (AFL) with 1:1 conduction. This may result in a wide QRS complex tachycardia due to use-
Miguel Aurrecoechea-Perea +4 more
doaj +1 more source
The disease mutation A77V in Ryanodine receptor RyR2 induces changes in energy conduction pathways in the protein [PDF]
, 2011 Energetically responsive residues of the 217 amino acid N-terminal domain of the cardiac Ryanodine receptor RyR2 are identified by a simple elastic net model. These residues lie along a hydrogen bonded path through the protein.
Burak Erman, Nazan Walpoth
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Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a +/− mouse model [PDF]
, 2011 Claire A. Martin +2 more
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