Results 101 to 110 of about 14,613 (227)
Multiple targets for flecainide action: implications for cardiac arrhythmogenesis [PDF]
Flecainide suppresses cardiac tachyarrhythmias including paroxysmal atrial fibrillation, supraventricular tachycardia and arrhythmic long QT syndromes (LQTS), as well as the Ca(2+) -mediated, catecholaminergic polymorphic ventricular tachycardia (CPVT ...
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Paranoid psychosis due to flecainide toxicity in malignant neuropathic pain.
Flecainide was used to treat malignant neuropathic pain but despite using therapeutic doses, toxicity occurred resulting in paranoid psychosis.
Bennett, Michael I.
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AGE-DEPENDENCE OF FLECAINIDE PHARMACOKINETICS
Aim: The aim of the study was to evaluate the relationship between age and the pharmacokinetics of flecainide. Methods: Fifteen patients with frequent premature ventricular contractions and with normal renal function were selected and divided into two ...
SPEDICATO L +6 more
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Background Vernakalant is authorized in several countries, except in the U.S., where the FDA denied its commercialization due to safety concerns, generating debate about its use.
Giuseppe Dominijanni +5 more
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Influence of left ventricular dysfunction on flecainide therapy [PDF]
Seventy-six patients with ventricular tachyarrhythmias (40 sustained and 36 nonsustained) were treated with oral flecainide. Radionuclide left ventricular ejection fraction was 30% or less in 33 patients and greater than 30% in 43 patients.
Horowitz, Leonard N. +6 more
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Background. In the Russian Federation, clinical experience with flecainide remains limited due to its relatively recent regulatory approval. Therefore, it is essential to evaluate the current safety and tolerability of this drug for the prevention of ...
L. V. Polischuk +3 more
doaj +1 more source
Background: Intravenous (IV) flecainide is recommended for the pharmacological cardioversion of recent-onset atrial fibrillation (AF). The aim of this study was to study the efficacy and safety of IV flecainide, co-administered with oral b-blockers, for ...
Athanasios Kartalis +9 more
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Altered flecainide disposition in healthy volunteers taking quinine.
The pharmacokinetics of flecainide and its two sequential metabolites, both free and conjugated, its pharmacodynamics, and the influence of simultaneously administered quinine, have been studied in 10 healthy subjects.
Reymond-Michel, G. +2 more
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Digoxin or flecainide for prophylaxis of supraventricular tachycardia in infants? [PDF]
Objectives.This study compared the safety and efficacy of digoxin and flecainide in the prophylaxis of supraventricular tachycardia in infants.Background.Recurrence of supraventricular tachycardia in infants is common. Digoxin is the conventional drug of
Gardiner, Helena M. +5 more
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Crystal Structure of Flecainide Acetate
Flecainide is antiarrhythmic drug. The structure of flecainide acetate, N-(2-piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate (C17H19F6N2O3) (C2H4O2), was determined by X-ray crystallography.
Mišņovs, Anatolijs +1 more
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