Results 101 to 110 of about 14,613 (227)

Multiple targets for flecainide action: implications for cardiac arrhythmogenesis [PDF]

open access: yes, 2017
Flecainide suppresses cardiac tachyarrhythmias including paroxysmal atrial fibrillation, supraventricular tachycardia and arrhythmic long QT syndromes (LQTS), as well as the Ca(2+) -mediated, catecholaminergic polymorphic ventricular tachycardia (CPVT ...

core   +2 more sources

Paranoid psychosis due to flecainide toxicity in malignant neuropathic pain.

open access: yes, 1997
Flecainide was used to treat malignant neuropathic pain but despite using therapeutic doses, toxicity occurred resulting in paranoid psychosis.
Bennett, Michael I.
core   +4 more sources

AGE-DEPENDENCE OF FLECAINIDE PHARMACOKINETICS

open access: yes, 1995
Aim: The aim of the study was to evaluate the relationship between age and the pharmacokinetics of flecainide. Methods: Fifteen patients with frequent premature ventricular contractions and with normal renal function were selected and divided into two ...
SPEDICATO L   +6 more
core  

Effectiveness and safety of vernakalant vs flecainide for cardioversion of atrial fibrillation in the emergency department: the VERITA study

open access: yesInternational Journal of Emergency Medicine
Background Vernakalant is authorized in several countries, except in the U.S., where the FDA denied its commercialization due to safety concerns, generating debate about its use.
Giuseppe Dominijanni   +5 more
doaj   +1 more source

Influence of left ventricular dysfunction on flecainide therapy [PDF]

open access: yes, 1987
Seventy-six patients with ventricular tachyarrhythmias (40 sustained and 36 nonsustained) were treated with oral flecainide. Radionuclide left ventricular ejection fraction was 30% or less in 33 patients and greater than 30% in 43 patients.
Horowitz, Leonard N.   +6 more
core   +1 more source

Safety and tolerability of flecainide for the prevention of atrial fibrillation: A systematic review and meta-analysis

open access: yesКубанский научный медицинский вестник
Background. In the Russian Federation, clinical experience with flecainide remains limited due to its relatively recent regulatory approval. Therefore, it is essential to evaluate the current safety and tolerability of this drug for the prevention of ...
L. V. Polischuk   +3 more
doaj   +1 more source

Acute Management of Paroxysmal Atrial Fibrillation with Intravenous Flecainide plus Oral Beta-Blockers

open access: yesInternational Journal of Translational Medicine
Background: Intravenous (IV) flecainide is recommended for the pharmacological cardioversion of recent-onset atrial fibrillation (AF). The aim of this study was to study the efficacy and safety of IV flecainide, co-administered with oral b-blockers, for ...
Athanasios Kartalis   +9 more
doaj   +1 more source

Altered flecainide disposition in healthy volunteers taking quinine.

open access: yes, 1990
The pharmacokinetics of flecainide and its two sequential metabolites, both free and conjugated, its pharmacodynamics, and the influence of simultaneously administered quinine, have been studied in 10 healthy subjects.
Reymond-Michel, G.   +2 more
core   +1 more source

Digoxin or flecainide for prophylaxis of supraventricular tachycardia in infants? [PDF]

open access: yes, 1995
Objectives.This study compared the safety and efficacy of digoxin and flecainide in the prophylaxis of supraventricular tachycardia in infants.Background.Recurrence of supraventricular tachycardia in infants is common. Digoxin is the conventional drug of
Gardiner, Helena M.   +5 more
core   +1 more source

Crystal Structure of Flecainide Acetate

open access: yes
Flecainide is antiarrhythmic drug. The structure of flecainide acetate, N-(2-piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate (C17H19F6N2O3) (C2H4O2), was determined by X-ray crystallography.
Mišņovs, Anatolijs   +1 more
core  

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