Results 81 to 90 of about 8,945 (197)

AGE-DEPENDENCE OF FLECAINIDE PHARMACOKINETICS

, 1995
Aim: The aim of the study was to evaluate the relationship between age and the pharmacokinetics of flecainide. Methods: Fifteen patients with frequent premature ventricular contractions and with normal renal function were selected and divided into two ...
SPEDICATO L, STROCCHI E, MAGNANI B., CAPUCCI A, CALLIVA R, BORIANI, Giuseppe, BIFFI M   +6 more
core  

Acute Management of Paroxysmal Atrial Fibrillation with Intravenous Flecainide plus Oral Beta-Blockers

International Journal of Translational Medicine
Background: Intravenous (IV) flecainide is recommended for the pharmacological cardioversion of recent-onset atrial fibrillation (AF). The aim of this study was to study the efficacy and safety of IV flecainide, co-administered with oral b-blockers, for ...
Athanasios Kartalis, Dimitrios Afendoulis, Petros Voutas, Maria Moutafi, Nikolaos Papagiannis, Stefanos Garoufalis, Nikolaos Kartalis, Nikolaos Smyrnioudis, Antonios Ziakas, Matthaios Didagelos   +9 more
doaj   +1 more source

Intentional Flecainide Overdose

, 2019
Flecainide acetate is a class 1C antiarrhythmic most often used for supraventricular arrhythmias. Intentional overdose of flecainide is rare and life threatening.
Singh, Gurjit, Grahf, Daniel, Babar Basir, Mir, Coriasso, Nicholas   +3 more
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Multiple targets for flecainide action: implications for cardiac arrhythmogenesis

, 2017
Flecainide suppresses cardiac tachyarrhythmias including paroxysmal atrial fibrillation, supraventricular tachycardia and arrhythmic long QT syndromes (LQTS), as well as the Ca(2+) -mediated, catecholaminergic polymorphic ventricular tachycardia (CPVT ...

core   +1 more source

Effectiveness and safety of vernakalant vs flecainide for cardioversion of atrial fibrillation in the emergency department: the VERITA study

International Journal of Emergency Medicine
Background Vernakalant is authorized in several countries, except in the U.S., where the FDA denied its commercialization due to safety concerns, generating debate about its use.
Giuseppe Dominijanni, Antonio F. Caballero-Bermejo, Ana Sainz-Herrero, Álvaro Pineda-Torcuato, Rosa Capilla-Pueyo, Belén Ruiz-Antorán   +5 more
doaj   +1 more source

Supraventricular tachycardia mimicking ventricular tachycardia during flecainide treatment

, 1988
As a class IC antiarrhythmic drug, flecainide can produce marked widening of the QRS complex. This effect is use dependent,1 indicating that widening of the QRS complex becomes more prominent during faster heart rates.
Lie, KI, VANGELDER, IC, van Gelder, IC, Crijns, HJ   +3 more
core   +1 more source

Influence of left ventricular dysfunction on flecainide therapy

, 1987
Seventy-six patients with ventricular tachyarrhythmias (40 sustained and 36 nonsustained) were treated with oral flecainide. Radionuclide left ventricular ejection fraction was 30% or less in 33 patients and greater than 30% in 43 patients.
Horowitz, Leonard N., Spielman, Scott R., Kay, Harold R., Senior, Sheila, de Paola, Angelo A.V., Morganroth, Joel, Greenspan, Allan M.   +6 more
core   +1 more source

Crystal Structure of Flecainide Acetate

Flecainide is antiarrhythmic drug. The structure of flecainide acetate, N-(2-piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate (C17H19F6N2O3) (C2H4O2), was determined by X-ray crystallography.
Mišņovs, Anatolijs, Stepanovs, Dmitrijs   +1 more
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Effects of flecainide on the electrophysiologic properties of isolated canine and rabbit myocardial fibers

, 1985
The electrophysiologic properties of flecainide, a new potent antiarrhythmic drug, are poorly defined. In this study, they were investigated by standard microelectrode technique in isolated cardiac muscle from rabbit and dog hearts. The concentrations of
Otto Hauswirth, Singh, Bramah N., Nobuo Ikeda, Larry D. Davis, Davis, Larry D., Bramah N. Singh, Ikeda, Nobuo, Hauswirth, Otto   +7 more
core   +1 more source

Antiarrhythmic treatment with flecainide (Tambocor). Clinical experience from 107 patients

, 1990
Udgivelsesdato: 1990-nullThe long-term clinical effect of oral flecainide treatment was evaluated in 107 pts (10-82 yrs). Indications for treatment were: atrial fibrillation 38%, atrial flutter 16%, ventricular tachycardia 24%, ventricular ectopic beats ...
Mickley, H, Pless, P, Møller, M, Frandsen, F   +3 more
core   +1 more source