Results 61 to 70 of about 14,613 (227)

Flecainide to Prevent Atrial Arrhythmia After Patent Foramen Ovale Closure: AFLOAT Study, A Randomized Clinical Trial

Circulation
BACKGROUND: The real incidence of atrial arrhythmia (AA) after patent foramen ovale (PFO) closure and whether this complication can be prevented remain unknown. We assessed whether flecainide is effective to prevent AA during the first 3 months after PFO
M. Hauguel-Moreau, P. Guedeney, Claire Dauphin, V. Auffret, Jean-Michel Clerc, E. Marijon, Meyer Elbaz, P. Aldebert, F. Beygui, Wissam Abi Khalil, A. da Costa, J. Macia, S. Elhadad, Guillaume Cayla, Xavier Iriart, M. Laredo, Thomas Rolland, Y. Temmar, Maria Elisabeta Gheorghiu, D. Brugier, J. Silvain, N. Hammoudi, G. Duthoit, A. Diallo, Éric Vicaut, G. Montalescot   +25 more
semanticscholar   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Paroxysmal atrial fibrillation recurrences and quality of life in symptomatic patients: A crossover study of flecainide and pilsicainide

Journal of Arrhythmia, 2017
Background: The therapeutic goals of atrial fibrillation (AF) patients are to reduce symptoms and prevent severe complications associated with AF. This study compared the efficacy of flecainide versus pilsicainide in reducing the frequency of AF and ...
Tsuyoshi Shiga, Koichiro Yoshioka, Eiichi Watanabe, Hisako Omori, Masahiro Yagi, Yasuo Okumura, Naoki Matsumoto, Kengo Kusano, Chikara Oshiro, Takanori Ikeda, Naohiko Takahashi, Takashi Komatsu, Atsushi Suzuki, Tsuyoshi Suzuki, Yasuto Sato, Takeshi Yamashita   +15 more
doaj   +1 more source

Feasibility, Safety, and Efficacy of Pulsed Field Ablation for Ventricular Arrhythmias: Insights From a Large Health System Registry in the United States

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging non‐thermal ablation modality with proven safety in atrial arrhythmia ablation. However, data on its performance for ventricular arrhythmias (VA) remain limited. Objective To evaluate the feasibility, safety, and efficacy of PFA for complex VA in a multicenter real‐world US registry ...
Narut Prasitlumkum, Juan F. Rodriguez‐Riascos, Hema Vemulapalli, Aakash Somappa, Camilo A. Estrada‐Vargas, Olubadewa A. Fatunde, Carlos A. Rojas, Poojan Prajapati, Keerthika Vijayakumar, Suraj Kapa, Duy Nguyen, Samuel Asirvatham, Malini Madhavan, Christopher McLeod, Hicham Z. El Masry, Abhishek J. Deshmukh, Danesh K. Kella, Ammar M. Killu, Siva K. Mulpuru, Mayank Sardana, Luis R. Scott, Alan M. Sugrue, Komandoor Srivathsan   +22 more
wiley   +1 more source

Intentional Flecainide Overdose [PDF]

, 2019
Flecainide acetate is a class 1C antiarrhythmic most often used for supraventricular arrhythmias. Intentional overdose of flecainide is rare and life threatening.
Singh, Gurjit, Grahf, Daniel, Babar Basir, Mir, Coriasso, Nicholas   +3 more
core   +1 more source

Zero‐Fluoroscopy Ablation Methods for Atrial Fibrillation: A Systematic Review and Meta‐Analysis

Pacing and Clinical Electrophysiology, EarlyView.
Central illustration. Schematic comparison of conventional fluoroscopy guided ablation (left) and zero fluoroscopy ablation (right), enabled by electroanatomical mapping and intracardiac echocardiography for catheter navigation without X ray. The study selection process is summarized (133 records identified; 12 studies included, total n = 1998 ...
Marwan Shawki, Ramzi Perdana Ilyas, Karanjeet Chauhan, Thalys Sampaio Rodrigues, Sarah Luna Nabhani, Gareth Wynn   +5 more
wiley   +1 more source

Antiarrhythmic Drug Therapy in Arrhythmogenic Right Ventricular Cardiomyopathy

Biomedicines, 2023
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable progressive myocardial disorder that predisposes patients to ventricular arrhythmias and sudden cardiac death.
Sean P. Gaine, Hugh Calkins
doaj   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger, Verena Charwat, Kevin E. Healy, Samuel Wall, Aslak Tveito   +4 more
wiley   +1 more source

Beta1-adrenoceptor polymorphism predicts flecainide action in patients with atrial fibrillation. [PDF]

PLoS ONE, 2010
BACKGROUND: Antiarrhythmic action of flecainide is based on sodium channel blockade. Beta(1)-adrenoceptor (beta(1)AR) activation induces sodium channel inhibition, too.
Amir M Nia, Evren Caglayan, Natig Gassanov, Tom Zimmermann, Orhan Aslan, Martin Hellmich, Firat Duru, Erland Erdmann, Stephan Rosenkranz, Fikret Er   +9 more
doaj   +1 more source