Results 51 to 60 of about 35,991 (298)
Alexander Fleck, Baron Fleck of Saltcoats, 1889-1968 [PDF]
Biographical Memoirs of Fellows of the Royal Society, 1971 Abstract Lord Fleck who died in London on 6 August 1968 was most widely known as a distinguished leader in chemical industry and as Chairman of Imperial Chemical Industries Ltd from 1953 to 1960. It was very apparent, however, to all with a closer acquaintance with him, that he could have been just as successful in other fields.
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Uma leitura da epistemologia de Ludwik Fleck: possíveis aproximações com o marxismo
AlexandriaEste trabalho, de caráter teórico, tem como objetivo buscar por aproximações entre o marxismo e a epistemologia de Ludwik Fleck, identificando pontos de convergências e divergências entre eles.
Marllon Moreti de Souza Rosa +1 more
doaj +1 more source
[STAMMBUCH MARIE FLECK] [Stammbuch Marie Fleck] ( - ) Cover ( - ) Einträge Bl. 1 - 10 (1) Einträge Bl. 11 - 20 (11) Einträge Bl. 21 - 30 (21) Einträge Bl.
Fleck, M.
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Ludwik Fleck: pesquisador e prisioneiro
Arquivo Maaravi: Revista Digital de Estudos Judaicos da UFMG, 2012 Quando o objetivo único de médicos e autoridades é desenvolver a ciência sem levar em conta os seres humanos, todos os caminhos ficam abertos para qualquer deformação, todas as regressões e degradações da desumanização tornam-se possíveis.
Ethel Mizrahy
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Brief von Eduard Fleck an Pauline Fleck
BRIEF VON EDUARD FLECK AN PAULINE FLECK Brief von Eduard Fleck an Pauline Fleck ( -
Fleck, Pauline, Fleck, Eduard
core +1 more source