Results 31 to 40 of about 35,991 (298)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Antiguos Jesuitas en Iberoamérica, 2016 One of the major conflicts involving the Society of Jesus in Paraguay Province, during the seventeenth century was not the issue involving the encomiendas and the bandeirantes invasions, but the conflict with the bishop of Asunción, the Franciscan priest
Gabriele Rodrigues de Moura
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Peroneal tendon dislocation in Talus fracture and diagnostic value of fleck sign
Foot & Ankle Orthopaedics, 2018 Category: Trauma Introduction/Purpose: INTRODUCTION: Talus fractures are not uncommon and one of the serious fractures in foot and ankle. Peroneal tendon dislocation is one of the commonly missed soft tissue injuries which may have significant impact on ...
Ahmed Attia MD +4 more
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HoST, 2020 Ludwik Fleck and Alfred Schutz each wrote groundbreaking treatises in the 1930s that laid the foundation for their views on the role of science education in establishing trust in science. This essay examines how science education was for Fleck explicitly
Olesko Kathryn M.
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Oral History Interview: Joseph Fleck [PDF]
, 2005 This interview is one of a series titled the Veterans History Project. Joseph Fleck was drafted in 1952. He discusses: being drafted; information about basic training and boot camp; moving across Europe in the service and his experiences in Germany and ...
Fleck, Joseph
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
PapelesIntrodução: No século XX, o campo da epistemologia recebeu relevantes contribuições do médico e microbiologista polonês Ludwik Fleck (1896-1961). O objetivo deste trabalho foi analisar como as categorias epistemológicas elaboradas por Fleck têm sido ...
Camila dos Santos Lima, Gabriel Ribeiro
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Prevalence of sweetpotato viruses in Acholi sub-region, northern Uganda
Current Plant Biology, 2019 The purpose of the study was to identify different viruses infecting sweetpotato and the level of co-infection and spatial distribution of the viruses within the Acholi sub-region of northern Uganda.
Godfrey Wokorach +3 more
doaj +1 more source