Results 31 to 40 of about 10,263 (261)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Peroneal tendon dislocation in Talus fracture and diagnostic value of fleck sign
Category: Trauma Introduction/Purpose: INTRODUCTION: Talus fractures are not uncommon and one of the serious fractures in foot and ankle. Peroneal tendon dislocation is one of the commonly missed soft tissue injuries which may have significant impact on ...
Ahmed Attia MD +4 more
doaj +1 more source
One of the major conflicts involving the Society of Jesus in Paraguay Province, during the seventeenth century was not the issue involving the encomiendas and the bandeirantes invasions, but the conflict with the bishop of Asunción, the Franciscan priest
Gabriele Rodrigues de Moura
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Ludwik Fleck and Alfred Schutz each wrote groundbreaking treatises in the 1930s that laid the foundation for their views on the role of science education in establishing trust in science. This essay examines how science education was for Fleck explicitly
Olesko Kathryn M.
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Prevalence of sweetpotato viruses in Acholi sub-region, northern Uganda
The purpose of the study was to identify different viruses infecting sweetpotato and the level of co-infection and spatial distribution of the viruses within the Acholi sub-region of northern Uganda.
Godfrey Wokorach +3 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Sociogênese do conhecimento e pesquisa em ensino: contribuições a partir do referencial Fleckiano
O trabalho aborda a teoria do conhecimento de Ludwik Fleck, analisando as origens e o contexto que orientaram sua produção, desde o contato com a Escola Polonesa de Filosofia da Medicina.
Demétrio Delizoicov +4 more
doaj
Tadeusz Bilikiewicz’s Background in the Debate with Ludwik Fleck
One of the factors that adversely influenced the worldwide reception of Fleck was the rather narrow critical interest that his ideas had aroused in Poland.
Artur Koterski
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