Results 61 to 70 of about 3,346,276 (367)

THE ROLE OF COORDINATED RESPONSE IN THE PERMANENCE OF ISLAMIC ARCHITECTURE

open access: yesMağallaẗ Al-kūfaẗ Al-handasiyyaẗ, 2022
Islamic architecture has been characterized by timelessness and eternity, due to the property of flexibility and the possibility of physical formation in different methods, while preserving its sanctity and this is represented by engineering and the ...
Riyam R. Fanjan, Ali M. AL-Khafaji
doaj   +1 more source

Introduction [PDF]

open access: yes, 2007
On December 1, 2006, the Department of Labor (“DOL”) issued a Request for Information (“RFI”) seeking public comments on the Family and Medical Leave Act (“FMLA”). The RFI was divided into three sections.
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Securing a Future: Cree Hunters' Resistance and Flexibility to Environmental Changes, Wemindji, James Bay

open access: yesEcology and Society, 2010
Accounts of the adaptive responses of northern aboriginal peoples include examples of purposive modification and management of ecologically favorable areas to increase resource productivity.
Jesse S. Sayles, Monica E. Mulrennan
doaj   +1 more source

Attendance Policies [PDF]

open access: yes, 2007
Part one of this memorandum provides a summary of questions asked and comments submitted in response to the DOL request for information ( RFI ) about attendance policies.
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Strengthening Intraframework Interaction within Flexible MOFs Demonstrates Simultaneous Sieving Acetylene from Ethylene and Carbon Dioxide

open access: yesAdvanced Science, 2023
Efficient separation of acetylene (C2H2)/ethylene (C2H4) and acetylene/carbon dioxide (CO2) by adsorption is an industrially promising process, but adsorbents capable of simultaneously capturing trace acetylene from ethylene and carbon dioxide are scarce.
Fang Zheng   +7 more
doaj   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

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