Results 61 to 70 of about 789,615 (268)

Flexible Employment, Flexible Families, And The Socialization Of Reproduction [PDF]

SSRN Electronic Journal, 2009
The progress of markets erodes traditional relations of social solidarity that are essential for the stability and performance of societies. As markets advance, pressures build on the state to replace informal social obligations with formal ones. Regulation may fail, however, which tends to give rise to demands for public services substituting for ...
openaire   +4 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Music-induced cognitive change and whole-brain network flexibility: a pilot study

Frontiers in Neuroscience
IntroductionCognitive impairment that exceeds age-related cognitive decline is a risk factor for Alzheimer’s disease and related dementias. As the older adult population is notably increasing every year, significant efforts are being made to preserve ...
E. Lydia Wu-Chung, Melia E. Bonomo, Anthony K. Brandt, Bryan T. Denny, Christof Karmonik, Christof Karmonik, J. Todd Frazier, Karl Blench, Christopher P. Fagundes, Christopher P. Fagundes, Christopher P. Fagundes, Christopher P. Fagundes   +11 more
doaj   +1 more source

Net Load Carrying Capability of Generating Units in Power Systems

Energies, 2017
This paper proposes an index called net load carrying capability (NLCC) to evaluate the contribution of a generating unit to the flexibility of a power system.
Chang-Gi Min, Mun-Kyeom Kim
doaj   +1 more source

Flexible Coinduction

, 2021
Recursive definitions of predicates by means of inference rules are ubiquitous in computer science. They are usually interpreted inductively or coinductively, however there are situations where none of these two options provides the expected meaning. In the thesis we propose a flexible form of coinductive interpretation, based on the notion of corules,
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Old and new forms of communication between the state and society on the way to a new social contract

RUDN journal of Sociology
The article considers the concept of social contract as a consensus between the state and the people. Based on the works of T. Hobbes, D. Locke, J.-J. Rousseau, C. Montesquieu, German social thought, in the context of reflections on the “legitimacy” of R.
R. I. Anisimov
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Evaluation of the Human Immunodeficiency Virus viral load surveillance system, national perspective in Tanzania: A descriptive cross-sectional study

Journal of Interventional Epidemiology and Public Health
Introduction: Human immunodeficiency virus (HIV) infection is still a global public health problem. The number of HIV-positive individuals was estimated to be 38.0 million worldwide in 2020, with 2.78 million being children and adolescents aged 0 to 19 ...
Peter Richard Torokaa, Loveness John Urio, Ambwene Mwakalobo, Alex Sifaeli Magesa, James Njoroge Allan, David John Osima, Focus Medard Shao, Joseph Mziray, Yulitha Barnabas, Agricola Joachim, Mtebe Majigo   +10 more
doaj   +1 more source