Results 71 to 80 of about 4,355,972 (307)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Monte Carlo simulations reveal the straightening up of an end-grafted flexible chain with a rigid side chain

, 2007
We have studied the conformational properties of a flexible end-grafted chain (length $N$) with a rigid side chain (length $S$) by means of Monte Carlo simulations.
A. Halperin, Dieter W. Heermann, K. Binder, Marcel Hellmann, Matthias Weiss   +4 more
core   +1 more source

Do flexible goal adjustment and acceptance help preserve quality of life in patients with Multiple Sclerosis? [PDF]

, 2015
Background Goal regulation strategies such as flexible goal adjustment and acceptance are believed to be protective factors in persons with chronic illness, but research on their relative contributions to quality of life in multiple sclerosis (MS) is ...
De Waegeneer, Annelies, Debruyne, Jan, Van Damme, Stefaan   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Flexible thermal apparatus for mounting of thermoelectric cooler [PDF]

, 1991
A flexible heat transfer apparatus used to flexibly connect and thermally couple a thermoelectric cooler to an object to be cooled is disclosed. The flexible heat transfer apparatus consists of a pair of flexible corrugated sheets made from high thermal ...
Bard, Steven, Jones, Jack A., Petrick, S. Walter   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Recent Development of Photochromic Polymer Systems: Mechanism, Materials, and Applications

Research
Photochromic polymer is defined as a series of materials based on photochromic units in polymer chains, which produces reversible color changes under irradiation with a particular wavelength.
Jindou Zou, Jimeng Liao, Yunfei He, Tiantian Zhang, Yuxin Xiao, Hailan Wang, Mingyao Shen, Tao Yu, Wei Huang   +8 more
doaj   +1 more source

Flexible, low-cost silicon solar cell arrays [PDF]

, 1972
Silicon solar cell arrays are pressure-bonded to flexible backing and protected by fluorinated ethylene propylene cover in one mechanized operation.
Bernatowicz, D. T., Broder, J. D., Forestieri, A. F.   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Bills Introduced in the 111th Congress Regarding Flexible Work Arrangements [PDF]

, 2009
Flexible Work Arrangements (FWAs) alter the time and/or place that work is conducted on a regular basis -- in a manner that is as manageable and predictable as possible for both employees and employers.
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source