Results 41 to 50 of about 67,126 (262)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Forced vibration of a sheet under periodic aerodynamic excitation
Nihon Kikai Gakkai ronbunshu, 2020 This paper describes vibration characteristics of a cantilevered flexible sheet under the periodic aerodynamic excitation. In the experiment, movable plates(exciter) are set at the upstream side from the sheet in a wind-tunnel.
Keiichi HIROAKI +2 more
doaj +1 more source
FullyPrinted Flexible Plasmonic Metafilms with Directional Color Dynamics
Advanced Science, 2021 Plasmonic metafilms have been widely utilized to generate vivid colors, but making them both active and flexible simultaneously remains a great challenge.
Jialong Peng +9 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Dynamics Characteristic Analysis of Sliding Bearing-rigid Rotor System with Flexible Support
Jixie chuandong, 2021 Considering the influence of nonlinear factors such as oil film force support of sliding bearing and external excitation of flexible support， a rigid rotor model with flexible supports at both ends is established.
Wenbin Wang
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Jixie chuandong, 2011 For the damping characteristic of the flexible coupling in high frequency is difficult to calculate and evaluate,based on the stress wave theory,the finite element analysis with the high frequency excitation for the flexible coupling model is carried out,
丁春华, 常山, 刘占生, 张广辉
doaj
IEEE Access, 2019 WFSM are included in the majority of large power generating units and special high-power motor drives, due to their high efficiency, flexible field excitation and intrinsic flux weakening capability.
Jonas Kristiansen Noland +3 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source