Results 41 to 50 of about 1,381,071 (297)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
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Review of Response and Damage of Linear and Nonlinear Systems under Multiaxial Vibration
Shock and Vibration, 2014 A review of past and recent developments in multiaxial excitation of linear and nonlinear structures is presented. The objective is to review some of the basic approaches used in the analytical and experimental methods for kinematic and dynamic analysis ...
Ed Habtour +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
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Numerical analysis of unsteady forces in a pump-jet propulsor due to dynamic tip-clearance changes
Zhongguo Jianchuan YanjiuObjectiveThis study aims to investigate the effects of dynamic variations in rotor tip-clearance on the unsteady forces of a pump-jet propulsor, while analyzing the role of a flexible isolation system in influencing the excitation characteristics of the ...
Huiyao LI +5 more
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Shock and Vibration, 2006 Flexible structures are frequently subjected to multiple inputs when in the field environment. The accurate determination of the system dynamic response to multiple inputs depends on how much information is available from the excitation sources that act ...
Paulo S. Varoto, Demian G. Silva
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Experimental Study on Streamwise Vortex-Induced Vibration of a Flexible, Slender Cylinder
Applied Sciences, 2018 Laboratory tests on streamwise vortex-induced vibration (VIV) of a flexible, slender cylinder were carried out in a towing tank. A cylinder model, 20 mm in diameter and 3.91 m in length, was towed horizontally to generate a uniform profile of relative ...
Wanhai Xu, Wenqi Qin, Xifeng Gao
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Forced vibration of a sheet under periodic aerodynamic excitation
Nihon Kikai Gakkai ronbunshu, 2020 This paper describes vibration characteristics of a cantilevered flexible sheet under the periodic aerodynamic excitation. In the experiment, movable plates(exciter) are set at the upstream side from the sheet in a wind-tunnel.
Keiichi HIROAKI +2 more
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FullyPrinted Flexible Plasmonic Metafilms with Directional Color Dynamics
Advanced Science, 2021 Plasmonic metafilms have been widely utilized to generate vivid colors, but making them both active and flexible simultaneously remains a great challenge.
Jialong Peng +9 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source