Results 31 to 40 of about 6,162 (305)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Pavement Management System Investigation in Case of Afghanistan

Cumhuriyet Science Journal, 2019
Afghanistanis encountering a massive compete in arrangement of old infrastructure.Specially for roads structure, it is found that many roads pavements built 30to 40 years ago and now it is the end of their life.
Sepanta Naımı, Mohammad Ali Karımı
doaj   +1 more source

Prediction of Surface Topography Parameters in Direct Laser Interference Patterning of Stainless Steel Using Infrared Monitoring and Convolutional Neural Networks

Advanced Engineering Materials, EarlyView.
This study presents an infrared monitoring approach for direct laser interference patterning (DLIP) combined with a convolutional neural network (CNN). Thermal emission data captured during structuring are used to predict surface topography parameters.
Lukas Olawsky, Marcelo Sallese, Leander Kläber, Clemens Kuhn, Keming Du, Andrés Fabián Lasagni   +5 more
wiley   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source

Improving Rutting Resistance of Pavement Structures Using Geosynthetics: An Overview

The Scientific World Journal, 2014
A pavement structure consists of several layers for the primary purpose of transmitting and distributing traffic loads to the subgrade. Rutting is one form of pavement distresses that may influence the performance of road pavements.
Sina Mirzapour Mounes, Mohamed Rehan Karim, Ali Khodaii, Mohammad Hadi Almasi   +3 more
doaj   +1 more source

Dimensionamento de um pavimento utilizando a técnica de pavimentação perpétua para um trecho da rodovia BR-282/SC [PDF]

, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Tecnológico. Engenharia Civil.A necessidade de uma abordagem ambiental no século XXI da construção civil tem fomentado o campo de pesquisas para encontrar métodos inovadores e duradouros ...
Grillo, Alexandre Henrique Hahn Franco
core  

Composition‐Tuned Enhancement of the Anomalous Nernst Effect in FeCo–Pt Thin Films on Rigid and Flexible Substrates

Advanced Engineering Materials, EarlyView.
Disordered (Fe50Co50)1−xPtx thin films exhibit a pronounced anomalous Nernst effect (ANE) with a strong composition dependence on both rigid and flexible substrates. The transverse thermoelectric response peaks near 22.5 at.% Pt, accompanied by enhanced αxy/σxy scaling, thermal transport, and ANE sensitivity.
Mojtaba Mohammadi, Hiroyuki Awano, Kenji Tanabe   +2 more
wiley   +1 more source

Investigation of Critical Aspects of Roughness Assessment for Airfield Pavements

Infrastructures
One of the main priorities of airport authorities is to maintain a high level of serviceability of runway pavements due to the high safety requirements for aircraft at high speeds.
Angeliki Armeni, Christina Plati, Andreas Loizos   +2 more
doaj   +1 more source

Effectiveness of Hybrid Geosynthetic Systems in Controlling Differential Heave in Flexible Pavements over Expansive Soils

Geotechnics, 2023
The challenge of maintaining ride quality and serviceability in flexible pavements built over expansive soil deposits remains a critical concern for transportation agencies.
Mir Md. Tamim, Debakanta Mishra, Bhaskar C. S. Chittoori   +2 more
doaj   +1 more source

A Lightweight Procedural Layer for Hybrid Experimental–Computational Workflows in Materials Science

Advanced Engineering Materials, EarlyView.
We unveil a prototype hybrid‐workflow framework that fuses automatedcomputation with hands‐on experiments. Built atop pyiron, a lightweight, parameterized layer translates procedure descriptions into executable manual steps, syncing instrument settings, human interventions, and data capture in real‐time today.
Steffen Brinckmann, Sarath Menon, Raphael Röske, Johannes Steinhülb, Michael Selzer, Jan Janssen, Tilmann Hickel, Ruth Schwaiger, Jörg Neugebauer   +8 more
wiley   +1 more source