Results 71 to 80 of about 8,142,265 (256)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Semi-Discretization of a Euler-Bernoulli Beam and Its Application to Motion Planning
IEEE AccessWe consider a Euler-Bernoulli beam with sliding cantilever boundary conditions at both ends. The control input to the beam is the force acting on one of the cantilevers.
Soham Chatterjee +2 more
doaj +1 more source
Relative positioning control of flexible structure for precise positioning stage
Mechanical Engineering Journal, 2020 Precise positioning technologies are widely used in industrial machines such as device manufacturing equipment. Many studies have been done on feedback control systems for precise positioning stages that improve accuracy by using sensor signal feedback ...
Hironori OGAWA +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Evaluation of an active force control for flexible structure
, 2010 The conventional method of suppressing the vibration by using passive damping which consists of mounting passive material on a structure will lead to increase the weight of the structure and hence decreasing the performance.
M. Yusup, Eliza
core
Flexible Pipes: Slug Flow and Structure Coupling [PDF]
, 2018 In this thesis, a computational scheme for coupled internal multiphase flow and structural dynamic of flexible pipes is presented and tested. The model consists of a 1D simulator based on a slug tracking model, and a 3D structural dynamic simulator based
Medina, Joaquín José Vieiro
core
A Time-History Contact Force Model of the Dynamic Load of AERORail Structures
Applied SciencesThis study proposes two curves that depict the vehicle–bridge contact force in a novel transportation system named AERORail, which is a lightweight cable-supported structure in which the rails and the prestressed cable form the load bearing system. Based
Fangyuan Li +3 more
doaj +1 more source
Vibration Control for Two Kinds of Flexible Mechanical Systems With Full State Output Constraints
IEEE Access, 2019 This paper concentrates on the vibration control problem of a flexible string system and a flexible Euler-Bernoulli beam system for considering full state output constraints, i.e., deflection and speed constraints.
Zhiqiang Lin +4 more
doaj +1 more source