Results 111 to 120 of about 5,905,568 (348)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The New South Wales Carers’ Responsibilities Act [PDF]

open access: yes, 2006
Enacted in 2001, the New South Wales Carers’ Responsibilities Act (“CRA”) prohibits discrimination against employees with caregiver responsibilities and provides access to reasonable flexible work arrangements. Under this law, employees have the right to
Georgetown Federal Legislation Clinic   +1 more
core   +1 more source

Flexible working: effects on women’s work-life balance, lifestyle and health [PDF]

open access: yes, 2018
Flexible working arrangement is a future work trends in response to growing concerns for evolving workforce demographics and retaining women in workforce.
Abdul Kadir, Adibah   +3 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Flexibility through working time accounts : reconciling economic efficiency and individual time requirements [PDF]

open access: yes
This paper discusses the tension between the demands of economic efficiency, on the one hand, and non-economic ends (leisure, family, etc.) on the other.
Seifert, Hartmut
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

NEW PATTERNS IN SCHEDULING WORKING TIME [PDF]

open access: yes
Flexible work arrangements should focus on providing employees with more options for when and how they do their work. Organizations can provide a suite of flexible options to enable employees to choose the arrangements that best balance their work with ...
Catalina Soriana SITNIKOV   +1 more
core  

Voluntary flexible working arrangements and their effects on managers and employees

open access: yes, 2020
This paper explores the effects of flexible working arrangements on employees and their managers in a service sector. Analyzing a case study of a global management consultancy, the study concerns the impact of flexible working arrangements on job ...
Stuart W. Sanders, Joanna Karmowska
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

More Pay and Benefits or Better Work-life Balance? Post Pandemic Perspectives on Employee Centricity among University Frontline Staff

open access: yesJournal on Efficiency and Responsibility in Education and Science
The COVID-19 pandemic forced organisations across diverse industries to redraw their business models globally. Businesses crumbled, downsized, lay off workers, streamlined and digitalized their workflow, maintaining skeletal staff to support integral ...
Phillip Dangaiso   +5 more
doaj   +1 more source

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