Results 101 to 110 of about 381,775 (307)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

FEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo, Emma Piccoli, Luca Bombardi, Martina Aulitto, Salvatore Fusco   +4 more
wiley   +1 more source

A Comparison of Five Animal Models for Acute Intervertebral Disc Herniation Research

JOR Spine
Study Design Microstructural investigation of mechanical load induced acute disc herniation on five animal models. Objective To compare how spinal discs in different animal models herniate under a standardized complex compressive load.
Thomas D. Slater, Beatrice Gagliostri, Matthew J. Kibble, Nazli S. Tümer, Peter A. Cripton, Nicolas Newell   +5 more
doaj   +1 more source

A substantial proportion of subjects with adolescent idiopathic scoliosis display spinal and peripheral proprioceptive deficits

Bone & Joint Open
Aims: Adolescent idiopathic scoliosis (AIS) is considered a multifactorial disease, and proprioceptive deficit (PD) is evident as a potential associated factor.
Kenney Ki Lee Lau, Kenny Yat Hong Kwan, Jason Pui Yin Cheung, Karlen Ka Pui Law, Arnold Yu Lok Wong, Daniel Hung Kay Chow, Kenneth Man Chee Cheung   +6 more
doaj   +1 more source

THE RELATIONSHIP BETWEEN MUSCULOSKELETAL STRENGTH, PHYSIOLOGICAL CHARACTERISTICS, AND KNEE KINESTHESIA FOLLOWING FATIGUING EXERCISE [PDF]

, 2012
Fatiguing exercise may result in impaired functional joint stability and increased risk of unintentional injury. While there are several musculoskeletal and physiological characteristics related to fatigue onset, their relationship with proprioceptive ...
Abt, John P, Allison, Katelyn Fleishman, Crawford, Kim, Lephart, Scott M, Lovalekar, Mita T, Nagle, Elizabeth F, Sell, Timothy C   +6 more
core  

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Bovine dystocia caused by carpal and shoulder flexion: A case report

Животновъдни науки
The term dystocia comes from the Greek (dys – difficult, tocos – birth). The condition represents the inability of the fetus to pass through the birth canal. Dystocia is a major cause of increased mortality during labor.
Aleksandar Apostolov, Aleksandar Stoimenov, Kalin Hristov   +2 more
doaj   +1 more source

Identifying Trippers and Non-Trippers Based on Knee Kinematics During Obstacle-Free Walking [PDF]

, 2018
Trips are a major cause of falls. Sagittal-plane kinematics affect clearance between the foot and obstacles, however, it is unclear which kinematic measures during obstacle-free walking are associated with avoiding a trip when encountering an obstacle ...
Benson, Lauren C., Cobb, Stephen C., Hyngstrom, Allison S., Keenan, Kevin G., Luo, Jake, O\u27Connor, Kristian M.   +5 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source