Results 81 to 90 of about 245,655 (314)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

The effect of transcranial direct current stimulation on perception of effort in an isolated isometric elbow flexion task [PDF]

, 2013
This is the author's manuscript as accepted for publication in Motor Control. The final published article is available from the link below, copyright @ 2013 Human Kinetics.The purported ergogenic actions of transcranial direct current stimulation (tDCS ...
Nowicky, AV
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Trunk inclinometer and L5 sEMG tracings demonstrating different flexion relaxation states: 2a) absent flexion relaxation, 2b) normal flexion relaxation.

, 2013
Trunk inclinometer and L5 sEMG tracings demonstrating different flexion relaxation states: 2a) absent flexion relaxation, 2b) normal flexion relaxation.
Jia-Hua Lin (319285), Raymond W. McGorry (319284)   +1 more
core   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Functional analysis of regenerated digit in newt following complete amputation at proximal interphalangeal joint

Journal of Biomechanical Science and Engineering
Amphibians possess high regeneration capacity of complicated structures such as articular joints. However, it is unknown when and how the joint function recovers during the regeneration process following a joint amputation. The present study examined the
Takeshi KASAHARA, Machiko TERAMOTO, Kiyokazu AGATA, Jeonghyun KIM, Takeo MATSUMOTO, Eijiro MAEDA   +5 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

How reliable are surgeons at assessing soft-tissue laxities in robotic arm-assisted total knee arthroplasty?: a prospective, multicentre surgeon-blinded study

Bone & Joint Open
Aims: Regardless of one’s alignment philosophy and belief in ligament releases, the precise estimation of soft-tissue laxities is crucial in total knee arthroplasty (TKA).
James A. Corbett, Darren B. Chen, Price Gallie, Anthony Leong, Jonathan S. Mulford, David Penn, Jil A. Wood, Samuel J. MacDessi   +7 more
doaj   +1 more source