Results 41 to 50 of about 245,655 (314)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The role of body segment movements on the control of centre of mass during balance corrections [PDF]

open access: yes, 2009
List of abbreviations: COM: centre of mass; CNS: central nervous system; SCA: Spinal Cerebellar Ataxia; APA: anticipatory postural activity. Human stance is an instable bipedal posture characterized by a high centre of mass (COM) located near the ...
Küng, Ursula Margareta
core   +1 more source

Flexionadductionexternal rotation method for shoulder dislocations

open access: yesActa Orthopaedica et Traumatologica Turcica, 2020
Objective: The aim of this prospective study was to assess the effectiveness of the flexion-adduction-external rotation method in the reduction of acute anterior shoulder dislocations. Methods: The study included 128 patients (98 male, 30 female; mean
Murat Gul   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The investigation of the folding quality in the printing house “BALTO“ / Lankstymo kokybės tyrimas UAB balto spaustuvėje

open access: yesMokslas: Lietuvos Ateitis, 2013
In the paper the folding quality in the printing house “BALTO”is investigated. The concept of quality, paper folding process,combined folding machine parameters and printing papers aredescribed.
Eglė Daujotaitė   +2 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A Clinical Study to Examine the Effect of Complete Denture on Head Posture/Craniovertical Angle [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Edentulous patients show some significant changes in ridge relationship caused by resorption of alveolar ridge. The changes are characterized by an upward rotation of mandible, increase in mandibular prognathism that ultimately results ...
Amit Khare   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Tibiofemoral and patellofemoral joint 3D-kinematics in patients with posterior cruciate ligament deficiency compared to healthy volunteers

open access: yes, 2012
Background: The posterior cruciate ligament (PCL) plays an important role in maintaining physiological kinematics and function of the knee joint. To date mainly in-vitro models or combined magnetic resonance and fluoroscopic systems have been used for ...
Ulrich Lenze   +15 more
core   +1 more source

La flexion et l’analytisme des substantifs en -a dans le dialecte du village de Gatnje, situe au sud du Kosovo [PDF]

open access: yesJužnoslovenski Filolog, 2012
Dans la presente etude, nous examinons la declinaison des substantifs feminins et masculins en-a dans le dialecte du village de Gatnje, situe au sud du Kosovo.
Mladenović Radivoje M.
doaj   +1 more source

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