Results 101 to 110 of about 112,673 (357)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
The Influence of External CFRP String Reinforcement on The Behavior of Flexural RC Elements
JGEET: Journal of Geoscience, Engineering, Environment and Technology, 2021 External reinforcement is an excellent method for improving the load carrying capacity and ductility behaviour of reinforced concrete members in flexure.
Junaedi Utomo +4 more
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Isostasy and Flexure of the Lithosphere
, 2023 Isostasy is a simple concept, yet it has long perplexed students of geology and geophysics. This fully updated edition provides the tools to better understand this concept using a simplified mathematical treatment, numerous geological examples, and an extensive bibliography.
openaire +2 more sources
Analysis of Flexural Strength and Contact Pressure After Simulated Chairside Adjustment of Pressed Lithium Disilicate Glass-Ceramic [PDF]
, 2018 Statement of problem Research evaluating load-to-failure of pressed lithium disilicate glass-ceramic (LDGC) with a clinically validated test after adjustment and repair procedures is scarce.
Berzins, David W. +3 more
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Flexure Revisited: Strength of Singly Reinforced Beams- A Simple Approach
مجلة النهرين للعلوم الهندسية, 2015 181 singly reinforced beam tests available from the literature are investigated to obtain two flexural design methods-one simple proposal and an alternative one that takes into account the influence of rising flexural reinforcement ratio on design.
Raid I. Khalel +3 more
doaj