Results 71 to 80 of about 112,673 (357)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Flexural behaviour of plain concrete prism strengthened by textile fine grained mortar [PDF]

, 2018
This paper presents a flexural strength study of concrete incorporated with textile fine grained mortar (TFGM) as a strengthening laminate. TFGM is a combination of fine grained mortar (FGM) with alkali resistant glass fabric (AR glass).
A. Khalid, Nur Hafizah, A. Majid, Masni, Abdul Hamid, Noor Azlina, Adnan, Suraya Hani, Jamellodin, Zalipah, Mohd Saman, Hamidah, Salleh, Norhafizah   +6 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Development of Ultrasonic Transducer with Flexure Hinge for Ultrasonic Spindle Milling [PDF]

, 2022
Rendi Kurniawan, Rendi Kurniawan, Minki Choo, Shou Chen, Yein Kwak, Saood Ali, Pilwan Han, Tae Jo Ko   +7 more
openalex   +1 more source

Acanthagrion marinae sp. Nov. (zygoptera: Coenagrionidae): A new species of the apicale group [PDF]

, 2018
Acanthagrion marinae sp. nov. (Holotype male: BRASIL, Mato Grosso do Sul, Campo Grande, UFMS, 20°29’56.26’’S-54°36’48.43’’W, 547m, leg. M.E. Rodrigues, 03.ii.2015, collection code: VZYG437, MLP) is described and illustrated on the basis of 15 males.
Lozano, Federico, Rodrigues, Marciel E
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Comprehensive Analysis of Ferrocement-Strengthened Reinforced Concrete Beam

Buildings
Starting with the premise that the choice of the optimal method for strengthening reinforced concrete (RC) structures is a complex task and that ferrocement strengthening is comparable to other advanced strengthening technologies due to its cost ...
Darko Živković, Predrag Blagojević, Danijel Kukaras, Radovan Cvetković, Slobodan Ranković   +4 more
doaj   +1 more source

Efficiency analysis of strengthening of RC structures with prestressed CFRP composites

Budownictwo i Architektura, 2013
The subject of the paper is the analysis of the efficiency of strengthening of RC structures for flexure with use of prestressed CFRP composites. Basic methods of application of the strengthening are described along with the issues connected with the ...
Renata Kotynia, Michał Staśkiewicz
doaj   +1 more source