Results 51 to 60 of about 173,287 (355)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Drag-compensated, precision-powered hinge system [PDF]

open access: yes, 1985
The design of a high precision powered hinge is complicated by the unavoidable presence of parasitic drag torque resulting mainly from friction and transfer of power, signals, and fluids across the hinge.
Jacquemin, G. G., Rusk, S. J.
core   +1 more source

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

open access: yesAdvanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian   +4 more
wiley   +1 more source

Hierachical micro/nano structures fabrication by a novel tri-axial piezoelectric servo system

open access: yesMaterials & Design, 2022
In this study, a novel tri-axial piezoelectric servo system is developed for micro/nano manufacturing considering the stroke, motion resolution, crosstalk, working bandwidth, compact structure, and position and pose modulation capability of cutting tool.
Haiqiang Yu   +6 more
doaj   +1 more source

Spectrally Tunable 2D Material‐Based Infrared Photodetectors for Intelligent Optoelectronics

open access: yesAdvanced Functional Materials, EarlyView.
Intelligent optoelectronics through spectral engineering of 2D material‐based infrared photodetectors. Abstract The evolution of intelligent optoelectronic systems is driven by artificial intelligence (AI). However, their practical realization hinges on the ability to dynamically capture and process optical signals across a broad infrared (IR) spectrum.
Junheon Ha   +18 more
wiley   +1 more source

Combined Compliance Calculation Method of the Flexure Hinge with Variable Cross Section and Its Verification

open access: yesJixie chuandong, 2017
The flexure hinge is the most basic compliant structure,the compliance is the most important performance parameter. The combined compliance method is proposed fully based upon the structure characteristic of the flexure hinge.
Guan Lixin, Liu Qingling
doaj  

An Inverse Kinematic Model for the 3-PRS Compliant Parallel Mechanism With Forward Causative Force

open access: yesIEEE Access, 2023
The inverse kinematic model is an essential mathematical tool of the performance analysis and motion control for the parallel mechanism. A diversity of mathematical methods is used for inverse kinematic modelling.
Junjie Wei   +3 more
doaj   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Structure Design and Optimization of Flexure Hinge Positioning Stage based on Giant Magnetostrictive Actuator

open access: yesJixie chuandong, 2017
A flexure hinge positioning stage with giant magnetostrictive actuator( GMA) as the driving unit is designed,which is composed of multi- group flexure hinges and guided by elastic deformation under force.
Mao Pengfei   +3 more
doaj  

Topological and Shape Optimization of Flexure Hinges for Designing Compliant Mechanisms Using the Level Set Method

open access: yesChinese Journal of Mechanical Engineering, 2019
A flexure hinge is a major component in designing compliant mechanisms that offers unique possibilities in a wide range of application fields in which high positioning accuracy is required.
Benliang Zhu   +4 more
doaj   +1 more source

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