Results 171 to 180 of about 260,704 (325)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Asymmetric synthesis of 4H-1,3-dioxins and investigations in the metal catalyzed aziridination: aziridination versus insertion and stereoselective course

ARKIVOC, 2007
Susanne Flock, Herbert Frauenrath
doaj   +1 more source

The role of ducks in detecting Highly Pathogenic Avian Influenza in small-scale backyard poultry farms. [PDF]

PLoS Comput Biol
Wu SX, Davis CN, Arnold M, Tildesley MJ.
europepmc   +1 more source

An analytical study on leader and follower switching in V-shaped Canada Goose flocks for energy management purposes

, 2020
Amir Mirzaeinia, Frank L. Heppner, Mostafa Hassanalian   +2 more
openalex   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Optimal flock formation induced by agent heterogeneity. [PDF]

Nat Commun
Montanari AN, Barioni AED, Duan C, Motter AE.   +3 more
europepmc   +1 more source

First and Second Cycle Egg Production Characteristics in Commercial Table Egg Flocks

, 1992
Donald D. Bell, Carol J. Adams
openalex   +1 more source

Viral analysis of tumor-bearing chicken flocks in Turkey over the last decade (2011-2020)

, 2023
A. Hasan, Şükrü Tonbak, Remziye Özbek, Burak Karabulut   +3 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A report of the in-farm variation of antimicrobial use in commercial broiler production in Pakistan using an international monitoring system based on treatment frequency. [PDF]

Front Vet Sci
Rehberg B, Brogden S, Fatima F, Umair M, Hartmann M, Kschonek J, Farooq U, Mohsin M, Kreienbrock L.   +8 more
europepmc   +1 more source