Results 61 to 70 of about 22,227 (242)

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon   +10 more
wiley   +1 more source

Autonomous House Floor Cleaning Robot

open access: yesInternational Journal of Recent Technology and Engineering, 2019
The biggest household issue is the cleaning of house or surrounding are without wasting much time but the cleaning process is laborious and time taking process, but for maintaining hygiene in house, house must be cleaned regularly. So, for keeping in mind this issue in this paper an autonomous cleaning robot is discussed, this robot works on predefined
openaire   +1 more source

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

open access: yesAdvanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding   +5 more
wiley   +1 more source

Additive‐Free Ti3C2Tx MXene Actuator with Large Deformation, Programmability, and High‐Humidity Stability via Precise Interlayer Spacing Control Engineering

open access: yesAdvanced Science, EarlyView.
By sequentially assembling MXene nanosheets with significant size differences, a multistimulus responsive additive‐free MXene actuator with gradient structure is obtained. An innovative cyclic low‐temperature annealing‐rehydration technology is proposed, which achieves precise control of interlayer d‐spacing, initial shape, and actuation behavior of ...
Haowen Zheng   +13 more
wiley   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

open access: yesAdvanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang   +18 more
wiley   +1 more source

Floor Cleaning Robot using Android App

open access: yesInternational Journal of Advanced Research in Science, Communication and Technology
The contemporary household landscape is witnessing a paradigm shift towards enhanced intelligence and automation. The integration of home automation systems not only provides increased convenience but also affords individuals more time for other pursuits.
null Dharam Chaitanya   +3 more
openaire   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

open access: yesAdvanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo   +3 more
wiley   +1 more source

Automatic Floor Cleaning Robot using Encoder

open access: yes, 2019
This research work is based on design and construction of a floor cleaning robot with two modes - automatic and manual mode. It supports automatic mode in this paper. IR sensor is used to avoid the obstacles and change left direction after right direction and it is mounted at the front side of the robot.
Kyawt Kay Thwe, Zaw Myo Tun
openaire   +1 more source

An Efficient Algorithm for Cleaning Robots Using Vision Sensors

open access: yesProceedings, 2019
In recent years, cleaning robots like Roomba have gained popularity. These cleaning robots have limited battery power, and therefore, efficient cleaning is important. Efforts are being undertaken to improve the efficiency of cleaning robots.
A. Ravankar   +3 more
semanticscholar   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

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