Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Structure of technogenous territories floras of the Donetsk region [PDF]
The research of structure of floras formed in various technogenous territories in the Donetsk region: iron and motorways, territories of metallurgical and coke-chemical plants, bread-making factories, ash dumps of the Zuev power station, a waste heap of ...
Тохтарь, В.К.
core +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Neotropical moss floras : species common to North and South America [PDF]
North and South America share about 675 species that show two basic patterns, namely, those with a continuous range and those with a disjunct distribution.
Delgadillo M., Claudio
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Impact of information technology on future floras [PDF]
Some important facilities offered by the information technology to innovate the development of traditional floras are illustrated and discussed. These include: random access interactive tools for the identification of species, low cost, easy updating ...
La Rosa, M +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Floristic Analysis of Vascular Plants in the Ziwuling Mountains, Shaanxi Province
A study was conducted on the vascular floras of the Ziwuling Mountains in Shaanxi Province to establish a foundational database, providing data support for the conservation and utilization of the Ziwuling Mountains’ plant diversity resources.
Shuyue Ma +5 more
doaj +1 more source
Plant Species Diversity in Jokhaneh Plain and Southern Slope of the Nil Mt. in Kohgilouyeh va Boyerahmad Province (Central Zagros Region of Iran) [PDF]
Plant species diversity in Jokhaneh plain and the southern slope of Nil Mt. is investigated in order to determine the flora and life forms and chorotypes of plants in this area. The studied area is located in Kohgilouyeh va Boyerahmad province, covers 22’
Maryam Parvizi +2 more
doaj +1 more source

