Results 51 to 60 of about 6,028 (261)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Floral Assemblages and Patterns of Insect Herbivory during the Permian to Triassic of Northeastern Italy.

open access: yesPLoS ONE, 2016
To discern the effect of the end-Permian (P-Tr) ecological crisis on land, interactions between plants and their insect herbivores were examined for four time intervals containing ten major floras from the Dolomites of northeastern Italy during a Permian-
Conrad C Labandeira   +2 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Comparative analysis of the local flora of Penza region

open access: yesИзвестия высших учебных заведений. Поволжский регион: Естественные науки
Background. The analysis of local floras reveals floristic diversity in most detail. This component of biodiversity is basic for its study and is important for solving scientific and practical problems. Materials and methods.
Anastasia V. Ivanova   +2 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Flora do Rio de Janeiro: Trigoniaceae

open access: yesRodriguésia, 2020
Resumo O levantamento taxonômico da Flora do estado do Rio de Janeiro revelou a presença de dois dos cinco gêneros que compõem a família de distribuição pantropical Trigoniaceae. O presente estudo teve como objetivo conhecer, divulgar e caracterizar está
João Rodrigues Miguel   +1 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Update and reassessment of the Miocene carpological flora from the Turów open pit mine of SW Poland and its palaeoenvironmental implications

open access: yesActa Palaeobotanica
One of the largest and best known, but never completely investigated, fossil carpological floras of the Zittau Basin is revised. The list of revised taxa is supplemented with materials left by H. Czeczott and her team, and newly collected specimens.
Rafał Kowalski   +2 more
doaj   +1 more source

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