Results 1 to 10 of about 13,748 (211)
Impacts of florfenicol on the microbiota landscape and resistome as revealed by metagenomic analysis [PDF]
Microbiome, 2019 Background Drug-resistant fish pathogens can cause significant economic loss to fish farmers. Since 2012, florfenicol has become an approved drug for treating both septicemia and columnaris diseases in freshwater fish.
Qifan Zeng +3 more
doaj +2 more sources
Similar Gastro-Intestinal Exposure to Florfenicol After Oral or Intramuscular Administration in Pigs, Leading to Resistance Selection in Commensal Escherichia coli [PDF]
Frontiers in Pharmacology, 2018 Florfenicol, which is licensed for veterinary use only, proves to be a potent antimicrobial for treatment of respiratory disease. However, the subsequent exposure of the gut microbiota to florfenicol is not well described.
Joren De Smet +6 more
doaj +5 more sources
Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing Enterococcus faecalis and Staphylococcus aureus [PDF]
Molecules, 2018 The optrA gene, which confers transferable resistance to oxazolidinones and phenicols, is defined as an ATP-binding cassette (ABC) transporter but lacks transmembrane domains. The resistance mechanism of optrA and whether it involves antibiotic efflux or
Yingyu Wang +5 more
doaj +3 more sources
Co-resistance and plasmid-mediated co-dissemination of florfenicol and azithromycin resistance in non-O157 Shiga toxin-producing Escherichia coli from cattle in Xinjiang, China [PDF]
BMC MicrobiologyBackground Florfenicol is a critical antibiotic used in cattle to manage respiratory infections, while azithromycin is recommended for treating early-stage Shiga toxin-producing Escherichia coli (STEC) infections.
Lei Wang +14 more
doaj +2 more sources
Oral pharmacokinetics of a pharmaceutical preparation of florfenicol in broiler chickens
Frontiers in Veterinary Science, 2023 IntroductionThe use of florfenicol must follow particular pharmacokinetic/pharmacodynamic (PK/PD) ratios, i.e., it requires achieving serum concentrations at or slightly above the pathogen's minimum inhibitory concentration (MIC) during the dosing ...
Lilia Gutierrez +4 more
doaj +1 more source
Frontiers in Veterinary Science, 2023 Florfenicol is used worldwide for its low side effects and strong bactericidal effect. Florfenicol is physicochemically stable and can persist in natural water bodies and affect water denitrification.
Tengyue Zhang +7 more
doaj +1 more source
Antibiotics, 2022 The overuse or abuse of antimicrobial drugs in aquaculture, aggravates the generation of drug-resistant bacteria, which has caused potential risks to human health and the aquaculture industry. Flavonoid–antibiotic combinations have been shown to suppress
Xianliang Zhao +5 more
doaj +1 more source
Antibiotics, 2022 This study aimed to determine the immunity, survival rate, and disease resistance of Litopenaeus vannamei treated using quercetin and florfenicol alone or in combination, after infection with acute hepatopancreatic necrosis syndrome caused by Vibrio ...
Qianqian Zhai +3 more
doaj +1 more source
Frontiers in Pharmacology, 2023 In two experimental trials; florfenicol pharmacokinetics following a single dose oral administration at 15 mg kg−1 fish body weight and biosafety through extended medicated feeding were studied in the rainbow trout, Oncorhynchus mykiss.
Sumanta Kumar Mallik +8 more
doaj +1 more source
Crystals, 2022 Florfenicol is an excellent antibiotic and is widely used in animal bacterial diseases. However, its poor water solubility leads to various problems, such as poor absorption and bioavailability.
Xinyuan Zhang +3 more
doaj +1 more source