Results 111 to 120 of about 537,328 (287)

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao, Long He, Yu Lu, Zanglong Deng, Hongzhen Wei, Yunpeng Zhang, Ming Yang, Tao Yin   +7 more
wiley   +1 more source

Effect of the hydrophobic fraction and particle size in the collectorless column flotation kinetics

, 1997
In order to investigate the particle size effect of a highly hydrophobic mineral (talc), different size fractions were floated in a column flotation cell to obtain the effect of flotation-rate constants (k) on the kinetics of flotation.
Sonmez, I, Yekeler, M, Meftuni Yekeler, ⌟brahim Sönmez, Yekeler, MEFTUNİ   +4 more
core   +1 more source

Pseudo‐Haptic Feedback: Multi‐Modal Approaches to Stiffness Perception and User Experience

Advanced Science, EarlyView.
Can visual deformation substitute for physical haptic feedback? In immersive VR, deformation‐based pseudo‐haptics enables stiffness discrimination comparable to wearable force feedback, while their combination yields the highest performance and presence without increasing workload.
Mehmet Ege Cansev, Xiaodong Sun, Gionata Salvietti, Domenico Prattichizzo, Philipp Beckerle   +4 more
wiley   +1 more source

Hypothalamic POMC Neurons Gate the Fear‐Feeding Trade‐Off

Advanced Science, EarlyView.
Hungry animals must continually arbitrate between feeding and defensive behaviors when confronted with potential threats. We show that hypothalamic POMC neurons engage CRH‐expressing stress circuits and downstream hormonal responses to coordinate this behavioral selection between competing behaviors.
Cristina Miralpeix, Abel Eraso‐Pichot, Vincent Simon, Victor Jouque, Melissa Sadallah, Samantha Clark, Philippe Zizzari, Urszula Skupio, Ana Covelo, Nathalie Dupuy, Jean Charles Nicolas, Astrid Cannich, Thierry Leste‐Lasserre, Guillaume Laplagne, Carmelo Quarta, Giovanni Marsicano, Daniela Cota   +16 more
wiley   +1 more source

Movement and distribution of particles in the tank of jet and agitation combined flotation machine

Meitan xuebao
In order to explore the movement and distribution of particles in the tank of jet and agitation co-flotation machine, a geometric model of the tank of jet and agitation co-flotation machine was established.
Tao WANG, Wei ZHOU, Zilei WANG, Shujie WANG, Lingling WANG, Liang LI   +5 more
doaj   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

The Application and Development of Microbubble Column Flotation Technology in China

, 2010
Since the early 1980s, great progress has been made in microbubble column flotation technology. As one of the important mineral processing methods, the application and development of this technology in China are summarized in this paper from four ...
Yong Tian Wang
core   +1 more source

Device Stochasticity Directly Implements Bayesian Sampling in Spiking Neurons

Advanced Science, EarlyView.
Brain‐inspired stochastic spiking turns device noise into Bayesian uncertainty for robust, low‐power neuromorphic computing. ABSTRACT Device stochasticity is considered a non‐ideality in neuromorphic hardware, although stochastic neural activity supports probabilistic computation in biological systems.
Huannan Zheng, Jingli Liu, Kezhou Yang
wiley   +1 more source

Accelerating High‐Fidelity Airfoil Design via Physics‐Informed Video Diffusion Model

Advanced Science, EarlyView.
Physics‐informed video diffusion enables rapid inverse aerodynamic design by mapping target lift‐to‐drag response to airfoil geometries and full‐field flow distributions. Trained on 53 400 DNS samples, the model achieves over 90% fidelity with ∼30 s inference, while experimentally realized propeller designs demonstrate a practical pathway from ...
Yifeng Ai, Yijia Guo, Hongfu Zhang, Lei Zhou, Tiejun Huang, Weiqiu Chen, Xuhui He, Peng Guo, C. W. Lim, Lei Ma   +9 more
wiley   +1 more source