Results 91 to 100 of about 3,893,973 (317)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Object-based 2D-to-3D video conversion for effective stereoscopic content generation in 3D-TV applications

open access: yes, 2011
Three-dimensional television (3D-TV) has gained increasing popularity in the broadcasting domain, as it enables enhanced viewing experiences in comparison to conventional two-dimensional (2D) TV.
Yue Feng   +8 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Share - Publish - Store - Preserve. Methodologies, Tools and Challenges for 3D Use in Social Sciences and Humanities

open access: yes, 2020
"Through this White Paper, which gathers contributions from experts of 3D data as well as professionals concerned with the interoperability and sustainability of 3D research data, the PARTHENOS project aims at highlighting some of the current issues they
Consortium 3D SHS Team
core   +1 more source

Numerical scour modeling around parallel spur dikes in FLOW-3D [PDF]

open access: yes, 2017
Abstract. Spur dikes are some structures which are built in the flow path with the aim of changing flow characteristics in order to bed and bank protection in rivers. These sudden changes in properties caused by the existence of spur dikes, produces erosion and sedimentation around them. In this paper, effects of series of parallel spur dikes have been
Pourshahbaz, Hanif   +2 more
openaire   +2 more sources

Vocabulaire 3D - Lexique pour les Sciences Humaines et Sociales

open access: yes, 2020
"Ce document est le résultat d’un effort continu pour permettre aux acteurs des SHS et ceux de la 3D d’interagir autour d’un vocabulaire commun. Ce lexique a pour but d’accompagner les différents livrables du consortium 3D.
Consortium 3D SHS Team
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

[Article] 3D digital recording of archaeological, architectural and artistic heritage

open access: yes, 2020
3D DIGITAL RECORDING OF ARCHAEOLOGICAL, ARCHITECTURAL AND ARTISTIC HERITAGE
Consortium 3D SHS Team
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Assessment of Turbulence Models on Bridge-Pier Scour Using Flow-3D

open access: yesWorld Journal of Engineering and Technology, 2019
The main purpose of this paper is to analyze the influence of different turbulence flow models on scouring pit of bridge-pier. Flow-3D software is applied in line with the purpose. The key motivation for this study is to contribute to the Flow-3D software by means of some modification and adjustment in the sediment scour model and shallow water model ...
Chandara Man   +4 more
openaire   +2 more sources

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