Results 81 to 90 of about 5,150,953 (307)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

بررسی خصوصیات جریان در محل تلاقی دو کانال مرکب (مطالعه عددی) [PDF]

open access: yesهیدرولیک
تلاقی رودخانه‌ها یا کانال‌ها، پدیده‌ای رایج است. اما علی‌رغم شباهت بیشتر مقاطع رودخانه‌ها به مقطع مرکب و نیز تفاوت‌های آن با مقاطع ساده، به نظر می‌رسد مطالعات جامعی در خصوص تلاقی دو کانال مرکب صورت نگرفته است. برای اعتبارسنجی مدل، نتایج شبیه‌سازی با داده‌
سید محمدمهدی عالمی   +1 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

آنالیز بررسی نیروهای هیدرودینامیکی در پرتاب کننده جامی سد (مطالعه موردی : سد جره) [PDF]

open access: yesهیدرولیک
سرریزها از اصلی‏ترین اجزاء سد می‏باشند که باعث کاهش انرژی مستهلک آب می‏گردند. از جمله سرریزهای که از لحاظ اقتصادی بسیار با صرفه می‏باشند، پرتاب کننده جامی می‏باشد.
غلامحسین اکبری   +3 more
doaj   +1 more source

Réaliser un projet de modèles numériques 3D pour le patrimoine. Guide de rédaction d'un cahier des charges

open access: yes, 2020
"Dans le cadre des activités du Consortium 3D de la TGIR Huma-Num, de nombreuses rencontres ont eu lieu réunissant des spécialistes aux profils divers (historiens, archéologues, informaticiens, architectes, ingénieurs 3D, archivistes …etc.) afin de ...
Consortium 3D SHS Team
core  

Computational Study of Flow around 2D and 3D Tandem Bluff Bodies

open access: yes, 2020
Numerical simulations have been carried out to advance our current understanding of flow around two dimensional (2D) and three dimensional (3D) square shaped tandem bluff bodies at a Reynolds number of 22,000, especially to shed light on the sudden ...
Yang, Z., Lu, Y., Charles, T.
core   +1 more source

pohl-michel/Lucas-Kanade-pyramidal-optical-flow-for-3D-image-sequences: 6th release

open access: yes, 2022
Implementation of the Lucas-Kanade pyramidal optical flow algorithm for registration of 3D medical images.
Pohl Michel
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Archéologie :imagerie numérique et 3D

open access: yes, 2018
Participation du CST3D SHS au séminaire scientifique organisé par l'IRISA /INRAP. Juin 2018 , Paris. Les communications du séminaire se sont concentrées sur les apports heuristiques de la modélisation 3D et de l’imagerie ...
Consortium 3D SHS Team
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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