Results 81 to 90 of about 7,237,339 (340)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Design and Modelling of 3D Bionic Cathode Flow Field for Proton Exchange Membrane Fuel Cell
Energies, 2021 Proton exchange membrane fuel cells (PEMFCs) have been utilized as a promising power source for new energy vehicles. Their performances are greatly affected by the structural design of the flow field in the bipolar plate.
Lingfeng Xuan +3 more
doaj +1 more source
Investigation of the existence of city-scale three-dimensional macroscopic fundamental diagrams for bi-modal traffic [PDF]
, 2013 Recent research has demonstrated that the Macroscopic Fundamental Diagram (MFD) is reliable and practical tool for modeling traffic dynamics and network performance in single-mode (cars only) urban road networks.
Ampountolas, K. +2 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Numerical study of the effect of trapezoidal obstacle in the mixing of muddy flow [PDF]
مهندسی منابع آب, 2020 muddy flows are gravitational flows, which are the difference in density or difference in weight of unit volume between two fluids due to suspended sediments.
Mohammad Givhighi +2 more
doaj
Scientific Reports, 2021 Long scan times prohibit a widespread clinical applicability of 4D flow MRI in Fontan patients. As pulsatility in the Fontan pathway is minimal during the cardiac cycle, acquiring non-ECG gated 3D flow MRI may result in a reduction of scan time while ...
Friso M. Rijnberg +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Numerical Study of Flow Pattern over Free Ogee Spillway (Case Study: Nimrod Reservoir Dam) [PDF]
مهندسی منابع آب, 2018 Spillways are structures used for releasing the surplus floodwater in necessary conditions from storage dams. Ogee spillway is one of the most common and simplest structures. .
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doaj
Numerical Simulation of Snow Deposition Around living Snow Fences [PDF]
, 2019 In this study, computational fluid dynamics (CFD) was used to investigate the air flow around porous snow fences to gain insight into snow transport and deposition in the vicinity of fences.
Petrie, John +2 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source