Results 41 to 50 of about 5,150,953 (307)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
3D Consortium: Creation, scientific use and archiving of 3D data for Humanities and Social Sciences
, 2020 "Dariah annual Event 23- 24 mai 2018. The 3D Consortium, accredited in 2014 by Huma-Num, brings together eleven partners working in the field of archaeology and cultural heritage and who already have experience of using 3D technologies and producing 3D ...
Consortium 3D SHS Team
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
مدلسازی آبشستگی پایین دست یک بند با استفاده از Flow-3D [PDF]
مجله مدل سازی در مهندسیدر مقالۀ حاضر نتاج حاصل از مدلسازی عددی عبور آب از روی یک بند و عمق و طول حفرۀ آبشستگی پایین‌دست آن با نتایج آزمایشگاهی انجام شده توسط Muhammad Abbas and Tanaka تحت شرایط هیدرولیکی مختلف شامل دو عمق بحرانی روی تاج سرریز (Dc) برابر 03/0 و 04/0 متر و دو ...
امیر قامتلو +1 more
doaj +1 more source
Conservatoire National de données 3D
, 2020 " Le Conservatoire National des Données 3D SHS est un environnement de sauvegarde sécurisé pour les données 3D, soutenu par Huma-Num. .
Consortium 3D SHS Team
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Numerical study of the effect of discharge on flow pattern around a submerged spur dike in an open channel [PDF]
مهندسی منابع آب, 2016 One of the important purposes of river engineering science is to protect river banks from erosion phenomenon and to prevent shifting of the main channel path.
Mohammad Vaghefi +2 more
doaj
بررسی تأثیر تنگ شدگی های قائم ورودی بر روی مشخصات هیدرولیکی شیب شکن قائم با استفاده از مدل عددی [PDF]
هیدرولیک, 2019 شیب شکن های قائم، سازه هایی هستند که در کانال های آبیاری، زهکشی، جمع آوری آب های سطحی استفاده می‌‌شوند. در تحقیق حاضر به بررسی عددی اثرات تنگ شدگی های قائم ورودی بر روی مشخصات هیدرولیکی شیب شکن با استفاده از نرم افزار FLOW-3D پرداخته شده است.
امیر قادری +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The Effects of Scales on Modeling of Flow Patterns Over Spillway [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعيةClimate changes leading to extreme events when the occurrence and intensity of severe phenomena have impeded the development and rehabilitation of hydraulic infrastructure, such as weirs and spillways according to these new conditions. The scale physical
Humam Khalid Ibrahim, Ammar Hatem Kamel
doaj +1 more source