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HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
This document presents a simulation-based study to understand flow boiling of water at low mass flux in a high aspect ratio microchannel subjected to constant wall temperature. In addition, numerical investigations are done to understand the influence of
Samia Sadaf, Fadi Alnaimat, Bobby Mathew
doaj +1 more source
Flow boiling and flow condensation are often regarded as two opposite or symmetrical phenomena involving the change of phase. There is a temptation to describe both these phenomena with one only correlation.
Mikielewicz Dariusz +2 more
doaj +1 more source
Prototype Boiling Ketupat Type of Batch Study of Heat Transfer Coefficient Into Condensor [PDF]
So far for producing ketupat done using boiling system open by using a regular steamer so much heat loss occurs due to his high consumption of fuel, to reduce the fuel consumption of the writers tried to make a prototype of a batch type boiling ketupat ...
Erlangga, R. (Reli)
core +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Numerical Investigation and Performance Evaluation of Boiling Slug Flow Regime of Water Vapor in Vertical Tubes [PDF]
The boiling phenomenon and two-phase flow regimes have provoked extensive research due to the increased heat transfer coefficient and significant industrial applications. In order to model correct heat transfer of boiling, it is important to simulate its
F. Sharifi, M. Hassani, R. Kouhikamali
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Oblique-finned microchannels have been reported to enhance heat transfer performance and suppress the flow boiling instability, but they can also cause an increase in pressure drop.
Juncheng Qiu +6 more
doaj +1 more source
Similarities and differences between flow boiling in microchannels and pool boiling [PDF]
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +1 more
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