Results 121 to 130 of about 834,813 (315)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Euler characteristic reciprocity for chromatic, flow and order polynomials [PDF]

, 2017
The Euler characteristic of a semialgebraic set can be considered as a generalization of the cardinality of a finite set. An advantage of semialgebraic sets is that we can define "negative sets" to be the sets with negative Euler characteristics ...
Hasebe, Takahiro, Toshinori Miyatani, Miyatani, Toshinori, Masahiko Yoshinaga, Takahiro Hasebe, Yoshinaga, Masahiko   +5 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Implicit Large-Eddy Simulations of Wall-Bounded Turbulent Flows. [PDF]

, 2007
The paper presents application of Implicit Large Eddy Simulation(ILES)to wall- bounded turbulent flows. A characteristics-based scheme in conjunction with total variation diminishing(TVD)Runge-Kutta time stepping and slope-limiting variants,for the com ...
Malick, Zeshan, Hahn, Marco, Shapiro, Evgeniy, Drikakis, Dimitris   +3 more
core  

Numerical study on the cerebral blood flow regulation in the circle of Willis with the vascular absence and internal carotid artery stenosis

Frontiers in Bioengineering and Biotechnology
ObjectivesThis study explores how vascular stenosis and absence affect the regulation of cerebral blood flow in the Circle of Willis (CoW) and the hemodynamic changes downstream of the stenosis.Materials and MethodsForty idealized CoW models were ...
Hong Lv, Hong Lv, Kailei Fu, Wei Liu, Zhiyi He, Zhiqing Li   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Vortex valve

EPJ Web of Conferences, 2018
The paper deals with a flow field inside the so-called vortex valve, used as an outlet device on retention reservoirs for retention of rainstorms and later slow outflow into sewerage etc. The system is very simple, without moving parts.
Adámek Karel, Kolář Jan, Peukert Pavel   +2 more
doaj   +1 more source

Characteristics of Debris Flow Cylindrical Flow Traces

, 2023
This is the data set and video of the debris-flow ...
openaire   +1 more source

Particle transport and deposition correlation with near-wall flow characteristic under inspiratory airflow in lung airways. [PDF]

Comput Biol Med, 2020
Farghadan A, Poorbahrami K, Jalal S, Oakes JM, Coletti F, Arzani A.   +5 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source