Results 151 to 160 of about 18,578,793 (360)
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Flow Characteristics of Slug Flow
Nobuo HATAKEYAMA, Karoku NODA
openaire +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effect of Pipe Wall Wear Defects on the Flow Characteristics of Slurry Shield Discharge Pipe
During slurry shield tunneling in hard rock or cobble strata, the discharge pipes suffer serve wear and damage. However, the effect mechanism of pipe wall wear defects on the flow characteristics of two-phase flow is unclear.
Yingran Fang +4 more
doaj +1 more source
CHARACTERISTICS OF TURBULENT FLOW
Turbulent flow is a complex and chaotic movement of fluid that occurs when a fluid moves at high velocities or interacts with solid boundaries. This phenomenon is critical in a wide range of scientific and engineering applications, such as in weather systems, industrial processes, and aerodynamics.
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The consumption of aquaculture products and, in turn, the importance of the aquaculture industry are increasing with the depletion of global fishery resources.
Jongjae Lee +5 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Simulation of a hydrocarbon fueled scramjet exhaust [PDF]
Exhaust nozzle flow fields for a fully integrated, hydrocarbon burning scramjet were calculated for flight conditions of M (undisturbed free stream) = 4 at 6.1 km altitude and M (undisturbed free stream) = 6 at 30.5 km altitude.
Leng, J.
core +1 more source

