Results 11 to 20 of about 2,666 (99)
Timothy F. Jamison at MIT developed (Org. Lett. 2013, 15, 710) a metal-free continuous-flow hydrogenation of alkene 1 using the protected hydroxylamine reagent 2 in the presence of free hydroxylamine. The reduction of nitroindole 4 to the corresponding aniline 5 using in situ-generated iron oxide nanocrystals in continuous flow was reported (Angew ...
Browne Duncan L.
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Chemistry in flow systems [PDF]
[No abstract available]
Andreas Kirschning
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Chemistry in flow systems II [PDF]
[No abstract available]
Andreas Kirschning
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Synthesis of Proteins by Automated Flow Chemistry [PDF]
Ribosomes produce most proteins of living cells in seconds. Here we report highly efficient chemistry matched with an automated fast-flow instrument for the direct manufacturing of peptide chains up to 164 amino acids over 328 consecutive reactions. The machine is rapid - the peptide chain elongation is complete in hours.
N. Hartrampf +17 more
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This is an editorial for a Special ...
Hessel, V, Ley, SV
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Special issue in flow chemistry [PDF]
In the last decade, we havewitnessed a steady transformation of organic chemistry. The number of launched new chemical entities decreased in spite of the number of synthetically accessible small molecules that exponentially increased. On the other hand, the drug like chemical space was only poorly sampled and the huge compound decks at Big Pharma ...
György M, Keseru, György, Dormán
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Organocatalysis Chemistry in Flow
The last decade has witnessed a huge growth in the use of flow chemistry as wellestablished procedure for performing chemical transformations; indeed, under continuous flow conditions, more sustainable, safer and easier scalable processes could be developed with respect to conventional batch procedures.
A. Puglisi +3 more
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Flash chemistry: flow chemistry that cannot be done in batch [PDF]
Flash chemistry based on high-resolution reaction time control using flow microreactors enables chemical reactions that cannot be done in batch and serves as a powerful tool for laboratory synthesis of organic compounds and for production in chemical and pharmaceutical industries.
Yoshida, Jun-ichi +2 more
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How to approach flow chemistry
The intrinsic attributes of flow chemistry that facilitate and provide reproducible access to a range of processes are best exploited using modules targeting an overall effect: a selective transformation or the generation of a reactive intermediate.
Mara Guidi +2 more
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