Results 61 to 70 of about 2,666 (99)
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2019
Historically pharmaceutical and fine chemical products have been synthesised using batch methods, but increasingly chemists are looking towards flow chemistry as a greener and more efficient alternative. In flow chemistry reactions are performed in a reactor with the reactants pumped through it.
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Historically pharmaceutical and fine chemical products have been synthesised using batch methods, but increasingly chemists are looking towards flow chemistry as a greener and more efficient alternative. In flow chemistry reactions are performed in a reactor with the reactants pumped through it.
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2017
Arturo Macchi of the University of Ottawa and Dominique M. Roberge of Lonza summarized (Org. Process Res. Dev. 2014, 18, 1286) a “toolbox approach” for the evolution from batch to continuous chemical synthesis. Michael D. Organ of York University developed (Org. Process Res. Dev.
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Arturo Macchi of the University of Ottawa and Dominique M. Roberge of Lonza summarized (Org. Process Res. Dev. 2014, 18, 1286) a “toolbox approach” for the evolution from batch to continuous chemical synthesis. Michael D. Organ of York University developed (Org. Process Res. Dev.
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2020
This chapter presents examples of and advocates for the adoption of tunable solid-state (semiconductor) oscillator single-mode microwave flow reactors toward laboratory and larger-scale synthetic chemistry applications. Tunable solid-state oscillator single-mode microwave flow reactors are more versatile heaters that impart both better process control ...
Joshua P. Barham +3 more
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This chapter presents examples of and advocates for the adoption of tunable solid-state (semiconductor) oscillator single-mode microwave flow reactors toward laboratory and larger-scale synthetic chemistry applications. Tunable solid-state oscillator single-mode microwave flow reactors are more versatile heaters that impart both better process control ...
Joshua P. Barham +3 more
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Continuous Flow Chemistry in Medicinal Chemistry
2011This chapter is intended to give the reader an introduction and insight into the principles of continuous flow chemistry, from the underlying concepts and potential benefits of performing chemical synthesis in this manner to some guidelines and advice on how to get started on running their own flow chemistry.
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2022
Chemical reactions are often carried out under mixing, especially at an industrial scale. Mixing aims to homogenize the concentrations and temperatures of reactants over a whole reactor, and therefore often requires a 3D flow and sometimes a 2D flow.
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Chemical reactions are often carried out under mixing, especially at an industrial scale. Mixing aims to homogenize the concentrations and temperatures of reactants over a whole reactor, and therefore often requires a 3D flow and sometimes a 2D flow.
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Flow chemistry provides unique advantages in organic synthesis, including allowing for greener or more atom-efficient routes, safer reaction setups, or enhanced product scaling. This [SynOpen](https://www.thieme.de/de/synopen/journal-information-102839.htm) Cheminar will explore a variety of topics in synthetic flow chemistry, with great speakers from ...
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C&EN Global Enterprise, 2017
Although continuous flow chemistry—wherein molecules are made in a continuous process rather than in batches—has gained ground in academic labs, its adoption by industry and contract manufacturing labs has been comparatively slow. Now, chemists at Eli Lilly & Co.
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Although continuous flow chemistry—wherein molecules are made in a continuous process rather than in batches—has gained ground in academic labs, its adoption by industry and contract manufacturing labs has been comparatively slow. Now, chemists at Eli Lilly & Co.
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2019
Continuous flow chemistry has many well-established advantages, including its facile automation, that make it an attractive technology for the rapid development and synthesis of target molecules. In this chapter, we highlight recent examples of automated continuous flow systems capable of chemical reaction optimization through the integration of ...
Jonathan N. Jaworski +2 more
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Continuous flow chemistry has many well-established advantages, including its facile automation, that make it an attractive technology for the rapid development and synthesis of target molecules. In this chapter, we highlight recent examples of automated continuous flow systems capable of chemical reaction optimization through the integration of ...
Jonathan N. Jaworski +2 more
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Flow chemistry is starting to flow
2012One good thing about this symposium on flow chemistry is that at least half of the papers was on actual applications: summarized one member of the audience of the IPIT symposium in Rotterdam, 25 May 2012. This remark can be viewed as a compliment to the organizer, TNO, a Dutch contract research organization.
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Towards the Standardization of Flow Chemistry Protocols for Organic Reactions
Chemistry Methods, 2021Christopher A Hone, Kappe C Oliver
exaly

