Results 131 to 140 of about 5,462,613 (380)

High resolution dual laser flow cytometry. [PDF]

, 1978
P. N. Dean, Daniel Pinkel
openalex   +1 more source

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

Molecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

HPLC and flow cytometry combined approach for HbF analysis in fetomaternal haemorrhage evaluation

Practical Laboratory Medicine
Introduction: Recently, a flow cytometric (FC) based test has been developed for detection of circulating fetal cells to replace the less accurate and reproducible Kleihauer-Betke test.FC test is easier to perform, it can distinguish the origin of fetal ...
Benedetta Peruzzi, Serena Guerrieri, Tiziana Biagioli, Luisa Lanzilao, Sara Pratesi, Sara Bencini, Marinella Statello, Alessia Carraresi, Stefania Stefanelli, Martina Tonelli, Marco Brogi, Manuela Capone, Alessio Mazzoni, Anna Maria Grazia Gelli, Alessandra Fanelli, Roberto Caporale, Francesco Annunziato   +16 more
doaj  

Imaging Flow Cytometry: Development, Present Applications, and Future Challenges

Methods and Protocols
Imaging flow cytometry (ImFC) represents a significant technological advancement in the field of cytometry, effectively merging the high-throughput capabilities of flow analysis with the detailed imaging characteristics of microscopy.
Savvas Dimitriadis, Lefkothea Dova, Ioannis Kotsianidis, Eleftheria Hatzimichael, Eleni Kapsali, Georgios S. Markopoulos   +5 more
doaj   +1 more source

Relevance of Antibody Validation for Flow Cytometry

Cytometry Part A, 2019
Antibody reagents are the key components of multiparametric flow cytometry analysis. Their quality performance is an absolute requirement for reproducible flow cytometry experiments.
T. Kalina, K. Lundsten, P. Engel
semanticscholar   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission

Nature Communications
Immune-mediated inflammatory diseases (IMIDs) are typically characterised by relapsing and remitting flares of inflammation. However, the unpredictability of disease flares impedes their study.
Kenneth F. Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel R. Schulz, Henrik E. Mei, Lucy MacDonald, Arthur G. Pratt, Andrew Filby, Amy E. Anderson, John D. Isaacs   +12 more
doaj   +1 more source

Breast Cancer and Tumor Microenvironment: The Crucial Role of Immune Cells

Current Oncology
Breast cancer is the most common type of cancer in women and the second leading cause of death by cancer. Despite recent advances, the mortality rate remains high, underlining the need to develop new therapeutic approaches.
Tânia Moura, Paula Laranjeira, Olga Caramelo, Ana M. Gil, Artur Paiva   +4 more
doaj   +1 more source

Label-free cell cycle analysis for high-throughput imaging flow cytometry

Nature Communications, 2016
Imaging flow cytometry combines the high-throughput capabilities of conventional flow cytometry with single-cell imaging. Here we demonstrate label-free prediction of DNA content and quantification of the mitotic cell cycle phases by applying supervised ...

semanticscholar   +1 more source

Laser flow cytometry and cancer chemotherapy: detection of intracellular anthracyclines by flow cytometry. [PDF]

, 1979
Awtar Krishan, Ram Ganapathi
openalex   +1 more source