Results 111 to 120 of about 796,572 (314)

Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission

Nature Communications
Immune-mediated inflammatory diseases (IMIDs) are typically characterised by relapsing and remitting flares of inflammation. However, the unpredictability of disease flares impedes their study.
Kenneth F. Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel R. Schulz, Henrik E. Mei, Lucy MacDonald, Arthur G. Pratt, Andrew Filby, Amy E. Anderson, John D. Isaacs   +12 more
doaj   +1 more source

Morphology and Flow Cytometry

, 2018
Despite the rapid development of molecular markers during the last years, the morphology of blood and bone marrow cells still keeps the crucial role for diagnosis and subclassification of the different subtypes of myelodysplastic syndromes (MDS), as recently confirmed by the new 2016 WHO classification [1].
Sockel, Katja, Kroschinsky, Frank, Oelschlaegel, Uta, van de Loosdrecht, Arjan A.   +3 more
openaire   +2 more sources

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Automation in high-content flow cytometry screening

, 2009
High-content flow cytometric screening (FC-HCS) is a 21st Century technology that combines robotic fluid handling, flow cytometric instrumentation, and bioinformatics software, so that relatively large numbers of flow cytometric samples can be processed ...
M. P. Wand, Wand, MP, U. Naumann, Naumann, U   +3 more
core   +1 more source

P068 | ABNORMAL CD33 EXPRESSION ON BLAST CELLS PREDICTS ELN2022 ADVERSE RISK ACUTE MYELOID LEUKEMIA

Haematologica
Multiparametric flow cytometry (MFC) is useful at diagnosis and during therapy by measuring minimal residual disease in acute myeloid leukemia (AML) patients (pts).
D. Bertoli, V. Giustini, C. Giupponi, V. Quaresima, D. Moratto, C. Cattaneo, G. Rossi, A. Tucci, D. Brugnoni, G. Biasiotto, E. Borlenghi, M. Chiarini   +11 more
doaj  

Breast Cancer and Tumor Microenvironment: The Crucial Role of Immune Cells

Current Oncology
Breast cancer is the most common type of cancer in women and the second leading cause of death by cancer. Despite recent advances, the mortality rate remains high, underlining the need to develop new therapeutic approaches.
Tânia Moura, Paula Laranjeira, Olga Caramelo, Ana M. Gil, Artur Paiva   +4 more
doaj   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source

Detection of mycoplasmas in goat milk by flow cytometry

, 2007
The detection of mycoplasma in milk can be performed by either culture techniques or polymerase chain reaction (PCR) based methods. Although PCR can reduce the average diagnostic time to 5 h in comparison with the several days for the isolation of the ...
Assunção, Patricia, Carlos M. Ruiz de Galarreta, De La Fe, Christian, Antunes, Nuno T., Davey, Hazel M., Rosales, Ruben S., Jose B. Poveda, Nuno T. Antunes, Ramirez, Ana S., Ruben S. Rosales, Hazel M. Davey, Poveda, Jose B., Ruiz De Galarreta, Carlos M., Ana S. Ramirez, Christian de la Fe, Patricia Assunção   +15 more
core   +1 more source

Challenges and Clinical Relevance in Diagnosing Metastatic Cells From Non‐Hematopoietic Malignancies in Bone Marrow Aspirates

Cancer Medicine
Introduction The causes of cytopenias are numerous, and the bone marrow aspirate helps to identify them. In rare cases, these cytopenias are due to bone marrow metastases from solid cancers.
Elise Kaspi, Charlotte Grosdidier, Yaël Berda‐Haddad, Maud Arpin, Sylvie Cointe, Shirley Fritz, Amandine Bonifay, Marie Koubi, Carine Jiguet‐Jiglaire, Patrice Roll, Diane Frankel   +10 more
doaj   +1 more source

Imaging Flow Cytometry: Development, Present Applications, and Future Challenges

Methods and Protocols
Imaging flow cytometry (ImFC) represents a significant technological advancement in the field of cytometry, effectively merging the high-throughput capabilities of flow analysis with the detailed imaging characteristics of microscopy.
Savvas Dimitriadis, Lefkothea Dova, Ioannis Kotsianidis, Eleftheria Hatzimichael, Eleni Kapsali, Georgios S. Markopoulos   +5 more
doaj   +1 more source