Results 131 to 140 of about 796,572 (314)

CD25+CD27+CD70− alloantigen-specific Tregs: promising stable immunotherapy for transplantation

Frontiers in Immunology
The clinical translation of alloantigen-specific regulatory T cells (AS-Tregs) is constrained by their low frequency in peripheral blood, limited purity, and functional instability following prolonged ex vivo expansion.
Arimelek Cortés-Hernández, Arimelek Cortés-Hernández, Saúl Arteaga-Cruz, Saúl Arteaga-Cruz, Iyari I. Martínez Iturbe, Iyari I. Martínez Iturbe, Katya Rosas-Cortina, Marco A. Vigil Mora, Marco A. Vigil Mora, Erick Legorreta-Anguiano, Erick Legorreta-Anguiano, Judith E. Reyes Barrientos, Judith E. Reyes Barrientos, Evelyn K. Álvarez-Salazar, Evelyn K. Álvarez-Salazar, Alejandra Cervera, Beatriz E. Sánchez-Hernández, Armando Gamboa Domínguez, Gloria Soldevila, Gloria Soldevila   +19 more
doaj   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Micro-impedance cytometry

, 2010
Electrical impedance spectroscopy is a non-invasive and label free technique that allows for rapid counting and characterisation of particles in suspension based on their response to applied AC potentials. In recent years, lab-on-a-chip technologies have
Bernabini, Catia
core  

Ole-Oxy, a Semi-Synthetic Analog of Oleuropein, Ameliorates Acute Skin and Colon Inflammation in Mice

Antioxidants
Inflammation is a key process in the pathophysiology of various diseases, with macrophages playing a central role in the inflammatory response. This study investigates the anti-inflammatory potential of a newly synthesized analog of oleuropein (OP), the ...
Nikolaos V. Angelis, Efthymios Paronis, Georgia Sarikaki, Antonios Kyriakopoulos, Anna Agapaki, Pigi-Maria Niotopoulou, Christina C. Knai, Pavlos Alexakos, Odyssefs Liagkas, Konstantinos F. Mavreas, Constantin N. Baxevanis, Alexios-Leandros Skaltsounis, Ourania E. Tsitsilonis, Ioannis K. Kostakis   +13 more
doaj   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

PB1994: COMPARISON OF PATIENTS WITH MYELODYSPLASTIC SYNDROMES WITH HIGH AND LOW OGATA SCORE VALUES ON CYTOMETRY IN RELATION TO THE PRESENCE OF CYTOGENETIC ABNORMALITIES - A PRELIMINARY STUDY

HemaSphere, 2023
Krzysztof Gawronski, Elżbieta Rutkowska, Iwona Kwiecień, Katarzyna Kulik, Alicja Dudzik, Agata Zakrzewska, Piotr Rzepecki   +6 more
doaj   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Flow cytometry: first principles

, 1992
xiv+202hlm ...
GIVAN, ALICE LONGOBARDI
core  

PB1991: NEW MONOCYTE HEMATOLOGICAL PARAMETERS AS AN IMPORTANT INDICATOR OF MDS PATIENTS WITH POSITIVE OGATA SCORE - A PRELIMINARY STUDY

HemaSphere, 2023
Alicja Dudzik, Katarzyna Kulik, Elżbieta Rutkowska, Iwona Kwiecień, Agata Raniszewska, Agata Zakrzewska, Krzysztof Gawronski, Waldemar Sawicki, Piotr Rzepecki   +8 more
doaj   +1 more source

Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke

Advanced Healthcare Materials, EarlyView.
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan, Damien Levard, Eloïse Lemarchand, Amal Boublay, Charly Helaine, Jolan Malherbe, Mikaël Naveau, Didier Goux, Igor Khalin, Ankita Talukdar, Cheun Pelleter, Charlène Jacqmarcq, Erwan Baudron, Isabelle Bardou, Sara Martinez de Lizarrondo, Maxime Gauberti, Denis Vivien, Antoine Philippe Fournier   +17 more
wiley   +1 more source