Results 231 to 240 of about 1,032,869 (292)

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Contribution of a specific panel by flow cytometry for the differential diagnosis of plasmacytoid dendritic cell neoplasms. [PDF]

Ann Hematol
Renosi F, Biichlé S, Roussel X, Fournet T, Roggy A, Pourchet V, Berry JF, Fredon M, Poussard M, Asnafi V, Macintyre E, Preudhomme C, Roumier C, Deconinck E, Daguindau E, Adotévi O, Angelot-Delettre F, Garnache-Ottou F.   +17 more
europepmc   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Causal Exposures of Immune Cells in Neuromyelitis Optica Spectrum Disorders: A Mendelian Randomization Study and Flow Cytometry Analysis. [PDF]

Brain Behav
Ren J, Wang J, Niu Z, Guo J, Zhang N, Hao H, Gao F, Liu R, Wang Z.   +8 more
europepmc   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Should the current diagnostic criteria for CLL be reconsidered? A reply to Johnstone et al. “De‐diagnosing chronic lymphocytic leukaemia: An ethical and scientific case for changing diagnostic criteria”

HemaSphere
Daniel Mazza Matos
doaj   +1 more source

Detection and quantification of rumen methanogens using F₄₂₀ autofluorescence profiling with spectral flow cytometry. [PDF]

Appl Environ Microbiol
Khanum S, Roberts JM, Della Rosa MM, Sage R, Reid PM, Soni P, Bagley S, Muetzel S, Janssen PH, Wedlock DN.   +9 more
europepmc   +1 more source

Utility of dual assessment of cyTRBC1 and cyTRBC2 by flow cytometry for identifying clonality in sCD3-negative to dimly expressing T cells. [PDF]

Blood Cancer J
Li M, Fu J, Li Y, Fan X, Zhang L, Zhou L, Zhang J, Zhang J, Xi Q.   +8 more
europepmc   +1 more source

Method comparison of microscopy, metabarcoding, and multispectral imaging flow cytometry for identification and relative abundance analysis of insect-dispersed pollen. [PDF]

Sci Rep
Motivans Švara E, Rakosy D, Knight TM, Keller A, Hornick T, Walther F, Dunker S.   +6 more
europepmc   +1 more source