Results 71 to 80 of about 2,271 (250)

Case Report: “Stent-within-a-Stent” technique after telescopic flow diverter reconstruction for basilar artery aneurysm with proximal stenosis

Frontiers in Surgery
BackgroundComplex basilar artery aneurysms are challenging to treat due to their deep anatomical location and proximity to critical perforating arteries, as well as their frequent fusiform morphology and association with long-segment stenosis or ...
Iroda Mammadinova, Chingiz Nurimanov, Nurtay Nurakay, Karashash Menlibayeva, Serik Akshulakov, Yerbol Makhambetov   +5 more
doaj   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

Management of intracranial aneurysms: a 2024 nationwide study from China

Journal of Stroke and Cerebrovascular Diseases
Background: Rising detection of unruptured intracranial aneurysms (UIAs) in China, driven by an aging population and increased neuroimaging utilization, coincides with significant regional disparities in neurointerventional resources.
Yu Gao, MS, Meihua Huyan, MD, Yina Wu, MD, Zhao Dai, MS, Yongwei Zhang, MD, Jianmin Liu, MD, Pengfei Yang, MD, Rui Zhao, MD, Qiang Li, MD   +8 more
doaj   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Yiting Jin, Zhimin Lv, Chao Bian, Qibin Yang, Na Zhou, Jianguang Qin, Shengming Sun   +6 more
wiley   +1 more source

Experience with the use of flow diverters in patients with arterial aneurysms in small vesseles

Українська Інтервенційна Нейрорадіологія та Хірургія
Objective ‒ to evaluate the results of treatment of patients with arterial aneurysms in small vesseles with flow diverters. Materials and methods. 18 patients with arterial aneurysms in small vesseles were treated in SO «Scientific-Practical Center of ...
D.V. Shchehlov, O.A. Pastushyn, O.Ye. Svyrydiuk, S.V. Konotopchyk, O.P. Kovalenko   +4 more
doaj  

Flow diverter-coil technique for endovascular treatment of complex wide neck brain aneurysms, Technical point

Caspian Journal of Internal Medicine, 2021
Background: Treatment of complex wide neck brain aneurysms is a challenging era in neurosurgery. Both surgical and endovascular therapies are considered for treatment of them. In endovascular, there are different ways such as trapping, coiling, stent and
Mohammad Ghorbani, Ebrahim Hejazian, Eshagh Bahrami, Abolghasem Mortazavi, Reza Bahrami, Nazila Farnoush   +5 more
doaj  

Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material

Advanced Science, EarlyView.
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao, Lijun Fan, Yunyuan Dong, Xuyu Bao, Xiaobin Chen, Qifu Zheng, Guanqing Zhang, Shen Wang, Wei Chen, Min Zhang, Shuaiming He   +10 more
wiley   +1 more source

Effects of film hole spanwise angle and diameter on flow and heat transfer of impingement/effusion cooling with crossflow diverters

Case Studies in Thermal Engineering
This paper studies the blade cooling under the co-effect of external film extraction and internal impingement cooling with crossflow diverters. The influence of spanwise angle (α) and diameter (Df) of film hole on flow and cooling performance are ...
Juan He, Kun Xiao, Haolong Li, Qinghua Deng, Hao Peng   +4 more
doaj   +1 more source