Results 61 to 70 of about 124,436 (288)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Non-WKB Models of the FIP Effect: The Role of Slow Mode Waves

, 2011
A model for element abundance fractionation between the solar chromosphere and corona is further developed. The ponderomotive force due to Alfven waves propagating through, or reflecting from the chromosphere in solar conditions generally accelerates ...
Allan, Avrett, Banaszkiewicz, Brooks, Bryans, Campos, Carlsson, Cranmer, Cranmer, Cranmer, Feldman, Feldman, Feldman, Ferland, Giammanco, Giammanco, J. Martin Laming, Kasper, Khomenko, Ko, Laming, Laming, Laming, Laming, Landau, Litwin, Patsourakos, Phillips, Schwadron, Sylwester, Sylwester, Widing, Wood   +32 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Investigation of tin adsorption on silica nanoparticles by using flow field-flow fractionation with offline inductively coupled plasma mass spectrometry

Journal of Analytical Science and Technology, 2018
Flow field-flow fractionation (Fl-FFF) for silica nanoparticles with offline inductively coupled plasma mass spectrometry (ICP-MS) was applied to investigate the adsorption behavior of tin onto silica nanoparticles.
Novy Lailatuz Zulfah, Atitaya Siripinyanond   +1 more
doaj   +1 more source

Internal fibre length concentration in a pressure screen [PDF]

, 2007
Localised axial consistency profiles within a pressure screen of a Pinus Radiata kraft pulp are reported. Axial Samples were also analysed using a Kajaani FS-200 to obtain fibre length distribution data.
Atkins, Martin John, Walmsley, Michael R.W., Weeds, Zuben   +2 more
core   +1 more source

Enantiomeric Ratio Changes of Terpenes in Essential Oils from Hybrid Eucalyptus grandis × E. tereticornis and its Pure Species [PDF]

, 2018
Some Eucalyptus species produce oils with biological activities and the effect of their interspecifc hybridization on the enantiomeric composition of terpenes has not been reported.
Alvarez Costa, Agustin, Gonzalez Audino, Paola Andrea, Lucia, Alejandro, Masuh, Hector Mario, Naspi, Cecilia Veronica   +4 more
core   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Silver nanoparticles as a medical device in healthcare settings: a five-step approach for candidate screening of coating agents [PDF]

Royal Society Open Science, 2018
Silver nanoparticle-based antimicrobials can promote a long lasting bactericidal effect without detrimental toxic side effects. However, there is not a clear and complete protocol to define and relate the properties of the particles (size, shape, surface
Valentina Marassi, Luisana Di Cristo, Stephen G. J. Smith, Simona Ortelli, Magda Blosi, Anna L. Costa, Pierluigi Reschiglian, Yuri Volkov, Adriele Prina-Mello   +8 more
doaj   +1 more source

Isospin fractionation in the nucleon emissions and fragment emissions in the intermediate energy heavy ion collisions

, 2003
The degree of isospin fractionation is measured by $(N/Z)_{n}$ / $(N/Z)_{N_{imf}}$, where $(N/Z)_{n}$ and $(N/Z)_{N_{imf}}$ are the saturated neutron-proton ratio of nucleon emissions (gas phase) and that of fragment emissions (liquid phase) in heavy ion
Aichelin, Aichelin, Alkahzov, Baran, Bertsch, Colonna, Danielewicz, Di Toro, Hang Liu, Jian-Ye Liu, Klakow, Kunde, Li, Li, Li, Li, Li, Liu, Liu, Liu, Miller, Pak, Pak, Pak, Pak, Rami, Reinhard, Sobotka, Sobotka, Tsang, Udo Schröder, Wada, Wen-Jun Guo, Westfall, Westfall, Xu, Yang, Yennello, Yennello, Yong Zhong Xing   +39 more
core   +1 more source

Proton Differential Elliptic Flow and the Isospin-Dependence of the Nuclear Equation of State [PDF]

, 2001
Within an isospin-dependent transport model for nuclear reactions involving neutron-rich nuclei, we study the first-order direct transverse flow of protons and their second-order differential elliptic flow as a function of transverse momentum.
A. Akmal, A. Akmal, A. Bonasera, A. Poskanzer, A.M. Lane, Andrew T. Sustich, B.A. Brown, B.A. Li, B.A. Li, B.A. Li, B.A. Li, B.A. Li, B.A. Li, B.A. Li, B.A. Li, B.D. Serot, Bao-An Li, Bin Zhang, C.J. Horowitz, D. Catalano, G.D. Westfall, G.D. Westfall, G.F. Bertsch, H. Heiselberg, H. Heiselberg, H. Huber, H. Huber, H. Müller, H. Stöcker, H. Xu, I. Bombaci, J. Zhang, J.-Y. Ollitrault, J.M. Lattimer, J.M. Pearson, L. Shi, M. Di Toro, M. Farine, M. Gyulassy, M. Veselsky, P. Danielewicz, P. Danielewicz, P. Danielewicz, P. Danielewicz, P.E. Haustein, P.F. Kolb, Q. Pan, R.B. Wiringa, S. Das Gupta, S.J. Yennello, V. Baran, W. Cassing, W. Udo Schröder, Z. Ren   +53 more
core   +3 more sources