Results 71 to 80 of about 4,365,776 (298)
Influence of spool diffusion profile on flow characteristics of turbine control valve
Zhongguo Jianchuan YanjiuObjectiveTo address the operational instability, vibration, and abnormal noise in a specific steam turbine unit, this study proposes a method for modifying the internal flow characteristics of the control valve through an internally-cut valve core ...
Luotao XIE +6 more
doaj +1 more source
, 2018 Topological implications of the total generalized electron-flow magnetic helicity He in electron magnetohydrodynamics(EMHD) are explored. The invariance of He is shown to imply the invariance of the sum of the linkage of the magnetic field lines, the ...
Michalak, M., Shivamoggi, B. K.
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Applied SciencesThe paper presents the results of investigations of flow velocity field distribution downstream of the nanofibrous filter in a minichannel determined by the particle image velocimetry (PIV) method.
Andrzej Krupa +3 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
The Influence of Interlocking Labyrinth Seal Cavity Dimension on Leakage
机车电传动, 2012 Taking the labyrinth seal of the transmission gearbox for a certain type of high-power locomotives as researching object, twodimensional structured grid model of the interlocking labyrinth channel was set up by means of software GAMBI.
王琰, 张开林, 王丽娜
doaj
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The average mean wind speed integrated over a disk is shown to be extremely close to the mean value of wind speed which would be measured at the center of a disk for most geometries in which a WECS (Wind Energy Conversion System) would operate.
Cliff, W. C., Verholek, M. G.
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source