Results 81 to 90 of about 3,868,108 (302)

Jet Propagation and Mach Cones in (3+1)d Ideal Hydrodynamics

, 2008
The observation of jet quenching and associated away--side Mach cone--like correlations at RHIC provide powerful ``external'' probes of the sQGP produced in A+A reactions, but it simultaneously raises the question where the jet energy was deposited.
Betz, Barbara, Gyulassy, Miklos, Rischke, Dirk H., Stöcker, Horst, Torrieri, Giorgio   +4 more
core   +1 more source

Stable Unitary Integrators for the Numerical Implementation of Continuous Unitary Transformations [PDF]

, 2017
The technique of continuous unitary transformations has recently been used to provide physical insight into a diverse array of quantum mechanical systems.
Refael, Gil, Savitz, Samuel
core   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Method for the evaluation of minor losses in pulsatile laminar fluid flow

EPJ Web of Conferences, 2014
This article focuses on description and evaluation of the size of the minor losses in pulsatile laminar flow. It describes a method for determination of minor losses with respect to the phase delay between pressure waveforms and flow waveforms. The whole
Netřebská H., Matěcha J., Schmirler M., Manoch L., Adamec J.   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The diagonal branches and outcomes in patients with anterior ST- elevation myocardial infarction

BMC Cardiovascular Disorders, 2020
Background The management of diagonal branch (D) occlusion is still controversary. The association between the flow loss of D and the prognosis remains unclear.
Shuning Zhang, Xin Deng, Wenlong Yang, Liping Xia, Kang Yao, Hao Lu, Lei Ge, Li Shen, Aijun Sun, Yunzeng Zou, Juying Qian, Junbo Ge   +11 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

On the effects of flow pulsation upon the performance of flow deflector for catalytic converter

Mechanical Engineering Journal, 2017
In automobile-exhaust systems, catalytic converters are the main components to produce substantial pressure drops, which induce engine-power loss and fuel-consumption rise. In addition to the need to reduce the pressure loss, the flow passing through the
Katsuya HIRATA, Shinya TANAKA, Masaya OTA, Taishi INOUE, Tomohiro OZAKI, Hirochika TANIGAWA   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source